The U.S. Senate voted overwhelmingly to support sweeping legislation that will, among other things, speed up the way the Food and Drug Administration approves new medicines. The bill will now go to President Barack Obama to sign into law.
ROME Italian Prime Minister Matteo Renzi resigned on Wednesday after a bruising referendum loss at the weekend, with most parliamentary factions pushing for an early election in a few months' time.
NEW YORK Wall Street surged on Wednesday, with the Dow industrials and S&P 500 hitting fresh records, as equities continued their march upward after the presidential election of Donald Trump and a new high for transportation stocks added to the bullish tone.
TORONTO Canadian yoga and leisure apparel retailer Lululemon Athletica Inc reported quarterly profit that beat analysts' forecasts on Wednesday, helped by higher-than-expected gross margins and sales, sending shares up 10 percent in extended trade.
BEIRUT Syrian rebels in besieged eastern Aleppo called on Wednesday for an immediate five-day ceasefire and the evacuation of civilians and wounded, but gave no indication they were ready to withdraw as demanded by Damascus and Moscow.
WASHINGTON A U.S. bank regulator is ready to fail Wells Fargo on a national scorecard for community lending, sources familiar with the decision said on Wednesday, in a move that could limit near-term expansion for the bank.