Pfizer, Bristol finalize deal on metabolic drugs
NEW YORK Aug 27 (Reuters) - Pfizer Inc. (PFE.N) and Bristol-Myers Squibb Co. (BMY.N) said on Monday they finalized an agreement reached in April, under which the drugmakers will research, develop and sell a class of medicines called DGAT-1 inhibitors.
The compounds could potentially treat metabolic disorders such as obesity and diabetes, the companies said. Pfizer had already discovered some such compounds in pre-clinical research, meaning early-stage studies not yet involving human subjects.
The partnership also includes DGAT-1 inhibitors that Pfizer licensed last year from German drugmaker Bayer AG BAYG.DE, including a pre-clinical compound known as PF-04415060, or BAY 74-4113.
As previously announced, Pfizer will be responsible for all early-stage studies under the Bristol-Myers deal, while the companies will jointly conduct Phase III -- or late-stage -- trials.
The companies said the compounds are designed to block DGAT-1, an enzyme that plays a big role in creation of blood fats called triglycerides which at high levels can make people more prone to diabetes and related problems.
((Reporting by Ransdell Pierson; Editing by Derek Caney; Reuters Messaging: firstname.lastname@example.org; 646-223-6034; email@example.com)) Keywords: PFIZER BRISTOLMYERS/
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