Protherics PLC announces Block Listing Return - 4

CHESHIRE, UK, Apr 10 (MARKET WIRE) --

Protherics PLC

6 monthly Block Listing Return

Unapproved Share Option Scheme

London, UK; Brentwood, TN; 10 April 2008 - Protherics PLC ("Protherics" or the
"Company"), the international biopharmaceutical company focused on critical care
and cancer, in accordance with Listing Rule 3.5.6, notifies the following
details in respect of the block listing for its Unapproved Share Option Scheme:

Name of applicant: Protherics PLC

Name of scheme: Protherics PLC
Unapproved Share Option Scheme

Period of return: From: 9 October 2007
To: 8 April 2008

Balance under scheme from previous return: 3,126,947

Plus: The amount by which the block scheme has been Nil
increased, if the scheme has been increased since the date
of the last return:

Less: Number of securities issued/allotted under scheme Nil
during period:

Equals: Balance under scheme not yet issued/allotted at 3,126,947
end of period

Number and class of securities originally listed and the 4,559,122 Ordinary
Shares (date of admission: 8 April 2005)
date of admission

Name of contact: Julie Vickers

Telephone number of contact: +44 (0) 1928 518010

| Ends |

For further information please contact:

Protherics
Nick Staples, Director of Corporate Affairs
+44 (0) 7919 480510
Julie Vickers, Company Secretary
+44 (0)1928 518010

Financial Dynamics - press enquiries
London: Ben Atwell, Lara Mott
+44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt
+1 212 850 5600

Or visit www.protherics.com

This information is provided by RNS
The company news service from the London Stock Exchange

Copyright 2008, Market Wire, All rights reserved.

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