Independent Confirmation That Menstrual Derived Stem Cells Have Utility in Fighting Disease

Wed Apr 23, 2008 9:40am EDT

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 Medistem Laboratories, Inc. (OTCBB: MDSM), a biotechnology company dedicated to
commercializationof its novel, universal donor, stem cell population, the
Endometrial Regenerative
Cell (ERC), applauds a recent publication from an independent Japanese group
describing a similar cell type to Medistem's ERC from the same source:
menstrual blood.

    The recent publication "Hida et al. Novel Cardiac Precursor-Like Cells
fromHuman Menstrual Blood-Derived Mesenchymal Cells. Stem Cells. 2008 Apr 17
[Epub ahead of print]" describes a stem cell population capable of not
onlybecoming heart tissue in vitro, but also having ability to repair injured
in animal models of heart attacks.

    "These recent data provide independent unbiased verification of the presence
of functional stem cells in the menstrual blood," said Thomas Ichim, CEO of
Medistem.  He continued, "Our previous publication and patent applications
describe a cell population with phenotypic and functional similarities to the
of Hida et al.  We are pleased to have aspects of our work successfully
reproduced and advanced by scientists at the prestigious Keio University
School of Medicine, Tokyo."

    In November 2007, an international group of scientists lead by Medistem
the discovery of the "Endometrial Regenerative Cell," a menstrual blood derived
stem cell that could differentiate into 9 major tissues, produce high levels of
therapeutic factors, and was capable of massive in-vitro expansion.  The study,
which is freely available at was awarded BioMed
Central's Best Publication in Medicine of 2007.

    "Medistem has more than 15 patent families dealing with adult stem cell
therapeutics.  The recent publication provides additional support for the
menstrual blood derived stem cell populations as a viable alternative to
embryonic stem cells," said Neil Riordan, Chairman of Medistem.

    About Medistem Laboratories

    Medistem Laboratories is a biotechnology company founded to develop and
commercialize technologies related to adult stem cell extraction, manipulation,
use for treating inflammatory and degenerative diseases. The company's lead
product, the endometrial regenerative cell (ERC), is a "universal donor"
stem cell derived from the menstrual blood that possesses the ability to
differentiate into nine tissue types, produce large quantities of growth
factors, and a large proliferative capacity. Due to Medistem's relationships
and collaborative efforts with respected institutions, Medistem believes it is
positioned to be a leading developer of adult stem cell products.

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Medistem Laboratories
Chris McGuinn

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