Overactive bladder affects many aspects of life

NEW YORK Thu Jun 12, 2008 5:25pm EDT

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NEW YORK (Reuters Health) - An overactive bladder has a considerable effect on the quality of life, work productivity, sexuality and the emotional well-being of men and women, U.S. and European researchers report in the journal BJU International.

Dr. Karin S. Coyne of United BioSource Corporation, Bethesda, Maryland and colleagues conducted a secondary analysis of data from a telephone survey involving participants from five countries.

The researchers matched 1,434 subjects who had an overactive bladder, with or without other lower urinary tract symptoms, to another 1,434 participants without overactive bladder or stress urinary incontinence who acted as a comparison group, or the "controls. "

The overactive bladder patients subjects reported significantly greater rates of chronic constipation, asthma, diabetes, high blood pressure, bladder or prostate cancer, neurological conditions and depression. There were also significant differences between the patients and controls in all reported lower urinary tract symptoms.

When the overactive bladder group was separated into subcategories, those who also had symptoms during and after urination reported being troubled significantly more by their symptoms than those in the other subgroups.

In addition, compared with the other subgroups, they had a poorer quality of life, higher rate of depression and decreased enjoyment of sexual activity.

The patients with overactive bladder plus other lower urinary tract symptoms appeared to be most affected, Dr. Coyne told Reuters Health. Therefore, "these conditions should be considered in conjunction in order to maximize treatment options and optimize patient outcomes."

SOURCE: BJU International, June 2008.

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