Study Finds Mannatech`s OsoLean Powder May Reduce Waist Circumference and Appetite in Overweight Adults

Results of Preliminary Study Published in "the Open Nutraceuticals Journal"
COPPELL, Texas--(Business Wire)--
Mannatech, Incorporated (NASDAQ:MTEX), a leading developer and provider of
proprietary dietary supplements, weight management products and skin care
solutions, today announced the results of a preliminary study indicating
Mannatech`s OsoLean powder, when supplemented with proper diet and exercise, may
result in decreased weight, BMI and waist circumference in healthy, overweight
adults.*

"We are pleased that this study, which provides further scientific evidence that
OsoLean powder can provide significant results in overweight adults striving to
maintain a healthy lifestyle, was published," said Chief Science Officer and
Senior Vice President of MannatechDr. Robert A. Sinnott, MNS. "Because Mannatech
is devoted to developing new wellness technologies with efficacy backed by
peer-reviewed human clinical trials, this study is very encouraging."

This preliminary, open-label, 8-week study of 112 overweight adults, published
March 16 in The Open Nutraceuticals Journal demonstrated that daily intake of
OsoLean powder appeared to reduce appetite, support weight loss and reduce waist
circumference(1).*

After being advised to restrict their daily caloric intake and add the
supplement to the beverage of their choice before breakfast and dinner, subjects
who participated in the study also completed quality of life questionnaires and
reported better appetite control and improved energy levels by the end of the
study.*

The study was conducted by Mannatech scientists in collaboration with
researchers in the Department of Biostatistics at the University of North Texas
Health Science Center in Fort Worth, Texas. To view the study findings, please
go to the Peer-Reviewed Science section of www.MannatechScience.org.

In a related 12-week, double-blind, placebo-controlled study published in 2008,
consumption of the same peptide blend in OsoLean powder in a flavored, sweetened
beverage, in conjunction with a 500-calorie reduced diet, helped to enhance fat
loss and retain lean muscle mass when compared to control subjects consuming a
placebo in addition to dieting.*

Follow-on studies are being planned to further explore the benefits of OsoLean
powder.

*This statement has not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure or prevent any disease.

(1) Full Citation: Sinnott RA, Maddela RL, Nelson EK, Bae S, Singh KP, Anderson
JA. The modifying effects of a calcium-rich whey protein supplement (OsoLeanTM
Powder) on weight loss and waist circumference in overweight subjects: a
preliminary study. Open Nutraceuticals J 2009; 2:36-41.

About Mannatech

Mannatech, Incorporated, is a global wellness solutions provider of innovative,
high-quality, proprietary dietary supplements, weight management products and
skin care solutions sold through independent Associates and Members located in
the United States and the international markets of Canada, Australia, the United
Kingdom, Japan, New Zealand, the Republic of Korea, Taiwan, Denmark, Germany,
South Africa, and Singapore. For more information please visit www.mannatech.com
or www.allaboutmannatech.com.

Please Note: This release contains "forward-looking statements" within the
meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of
the Securities Exchange Act of 1934, as amended, and the Private Securities
Litigation Reform Act of 1995. These forward-looking statements generally can be
identified by use of phrases or terminology such as "intend" or other similar
words or the negative of such terminology. Similarly, descriptions of
Mannatech`s objectives, strategies, plans, goals or targets contained herein are
also considered forward-looking statements. Mannatech believes this release
should be read in conjunction with all of its filings with the United States
Securities and Exchange Commission and cautions its readers that these
forward-looking statements are subject to certain events, risks, uncertainties,
and other factors. Some of these factors include, among others, Mannatech`s
inability to attract and retain associates and members, increases in
competition, litigation, regulatory changes, and its planned growth into new
international markets. Although Mannatech believes that the expectations,
statements, and assumptions reflected in these forward-looking statements are
reasonable, it cautions readers to always consider all of the risk factors and
any other cautionary statements carefully in evaluating each forward-looking
statement in this release, as well as those set forth in its latest Annual
Report on Form 10-K and Quarterly Report on Form 10-Q, and other filings filed
with the United States Securities and Exchange Commission, including its current
reports on Form 8-K. All of the forward-looking statements contained herein
speak only as of the date of this release.

Mannatech
Kristen Ridgway, 972-471-7221
Corporate Communications
kridgway@mannatech.com
or
Media Contact:
HCK2 Partners for Mannatech
Erin Groover, 972-716-0500, ext. 41
erin.groover@hck2.com
www.mannatech.com
www.exploremannatech.com
www.allaboutmannatech.com

Copyright Business Wire 2009