Health and Advocacy Leaders Mobilize to Bring Attention to Atrial Fibrillation, a...

Health and Advocacy Leaders Mobilize to Bring Attention to Atrial
Fibrillation, a Costly and Misunderstood Cardiovascular Disease

Survey Shows Patient and Healthcare Professionals are 'Out of Sync' About
Potential Serious Health Consequences

WASHINGTON, May 18 /PRNewswire-USNewswire/ -- As the nation's 76 million Baby
Boomers approach their Medicare years, a diverse group of healthcare leaders
today joined together to launch AF Stat(TM): A Call to Action for Atrial
Fibrillation (AF Stat), and announce the formation of the AF Stat Working
Group. This first-of-its-kind, national initiative aims to elevate
understanding, diagnosis and management of atrial fibrillation (AFib) among
all those affected by this serious and increasingly prevalent cardiovascular
disease.

Approximately 2.5 million Americans currently have AFib, but because the risk
increases with age, this number is expected to rise dramatically as the U.S.
population gets older(1). Characterized by a very irregular and frequently
fast heart rate, AFib is associated with a five-fold increase in risk for
stroke(2); worsens underlying cardiovascular disease(3) and doubles the risk
of all-cause mortality(4). It also costs the nation $6.65 billion annually,
much of which could be attributed to the increased hospital in-patient,
emergency and medical services utilization rates for people with AFib(5).

"Reducing the impact of chronic diseases is an essential component to health
reform discussions," said Senator Bill Frist, M.D., who joined the AF Stat
Working Group in the role of health policy advisor. "Per-patient medical
costs have been found to be as much as five times more for AFib patients than
those without the disease, and the impact disproportionately affects Medicare
and Medicaid budgets. A collaborative effort like AF Stat will help uncover
better ways to address this manageable disease, and could be an important step
in lessening its burden on patients and our healthcare system."

The AF Stat Working Group brings together leaders representing 24 advocacy,
medical professional, aging, caregiver, employer, payer and cardiovascular
organizations. The group's first goal is to draft an AF Call to Action
outlining the barriers and priority steps needed to improve AFib management.
The group will then work together to implement those actions.

"AFib is emotionally and physically draining and the risks are potentially
debilitating," noted NBA Hall of Famer Jerry West, legendary former player,
coach and general manager of the Los Angeles Lakers. "I've always been active
and in control and cannot imagine how life would be if I suffered a stroke.
My biggest fear is to no longer be physically viable and become a burden on my
family. That was a huge motivator in how thoroughly I researched AFib even
though there was not a lot of information out there."

"Out of Sync: The State of AFib" Survey
Today's release of a survey measuring physician, nurse and patient AFib
experiences and attitudes, "Out of Sync: The State of AFib", shows that Mr.
West is not alone in his search for information, reinforcing the need for AF
Stat.

The survey measured the experiences and attitudes of physicians, nurses and
patients with AFib. The results indicate a clear disconnect between medical
professionals and patients about their understanding of AFib and its risks,
demonstrating a need for better educational resources:

-- Less than half of AFib patients fully appreciate or recognize the
health
consequences of the condition, particularly their increased risk of
stroke and heart failure:
-- While almost all physicians (97 percent) think their AFib patients
are at severe/moderate risk of stroke, less than half (45 percent)
of AFib patients think they are at risk.
-- More than 90 percent of physicians think their AFib patients are
at
severe/moderate risk of death from heart-related causes. In
contrast, fewer than 40 percent of patients think they are at
risk.

-- More than half of doctors (53 percent) believe there is a lack of
available support and materials for patients with AFib; 42 percent of
doctors reported having to use their own drawings, as opposed to using
charts, posters or anatomical models, to guide patient discussions
about
AFib, while nurses report using their hands or charts/posters(6).

"The complex nature of AFib requires individualized patient care and is a
major barrier to optimal management and underscores the need for comprehensive
education on AFib for a wide range of audiences," said Eric Prystowsky, M.D.,
AF Stat Medical Chair and director of the Clinical Electrophysiology
Laboratory, St. Vincent Hospital in Indianapolis. "AF Stat will begin to fill
awareness and educational gaps and identify quality and policy measures, which
will hopefully lead to better patient outcomes."

About the "Out of Sync" Survey
"Out of Sync: The State of AFib in America" survey was conducted by
Yankelovich, part of the Futures Company, to compare the perspectives of
patients who have been diagnosed with AFib, and the physicians and nurses who
treat the patients with the disease. Survey results were obtained through
online interviews among 200 doctors and 200 nurses who treat AFib patients,
and 500 AFib patients, representative of a national sample. Interviews took
place between March 13 - 20, 2009.

About AF Stat(TM): A Call to Action for Atrial Fibrillation
AF Stat is a collaboration of healthcare leaders and organizations working to
improve the health and well-being of people affected by atrial fibrillation.
AF Stat is raising awareness of AFib as a complex, costly, progressive and
often debilitating disease. It also is calling for and helping promote a
change in attitudes and behaviors to enhance AFib understanding, diagnosis and
management. AF Stat is an initiative sponsored by sanofi-aventis U.S. LLC.

AF Stat(TM): A Call to Action for Atrial Fibrillation is an initiative
sponsored by sanofi-aventis U.S. LLC

(1) Go, A. Prevalence of Atrial Fibrillation in Adults: National Implications
for Rhythm Management and Stroke Prevention: The AnTicoagulation and Risk
Factors in Atrial Fibrillation (ATRIA) Study. JAMA, May 9, 2001-Vol 285, No.
18.

(2) Wolf PA, Abbott RD, Kannel, WB. Atrial fibrillation as an independent risk
factor for stroke: the Framingham Study. Stroke. 1991;22;983-988.

(3) Fuster V, Ryden LE, Cannom DS, et al.
ACC/AHA/ESC 2006 Guidelines for the Management of Patients with Atrial
Fibrillation: a report of the American College of Cardiology/American Heart
Association Task Force on Practice Guidelines and the European Society of
Cardiology Committee for Practice Guidelines (Writing Committee to Revise the
2001 Guidelines for the Management of Patients With Atrial Fibrillation):
developed in collaboration with the European Heart Rhythm Association and the
Heart Rhythm Society. Circulation. 2006;114:e257-e354.

(4) Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D.
Impact of atrial fibrillation on the risk of death: the Framingham Heart
Study. Circulation. 1998;98:946-952.

(5) Coyne KS, Paramore C, Grandy S, Mercader M, Reynolds MR, Zimetbaum P.
Assessing the direct costs of treating nonvalvular atrial fibrillation in the
United States. Value Health. 2006;9:348-356.

(6) Out of Sync: The State of AFib in America Survey. Conducted by
Yankelovich, Part of the Futures Company March-April, 2009. Sponsored by
sanofi-aventis.

SOURCE AF Stat Working Group

Tom Murphy of AF Stat Working Group, +1-202-368-8571, tmurphy@ccapr.com