Vical to Present At Upcoming Investor Conferences

SAN DIEGO, June 1, 2009 (GLOBE NEWSWIRE) -- Vical Incorporated (Nasdaq:VICL)
today announced that the company's President and Chief Executive Officer, Vijay
B. Samant, will provide an overview of the company's technologies, development
programs, and strategic partnerships at two upcoming investor conferences:

-- The Noble Financial Group Fifth Annual Equity Conference: Austin
Power Brokers (Hollywood, FL, June 8 - 9);

-- The 8th Annual Needham Life Sciences Conference: Healthcare Today
& Tomorrow (New York, June 10 - 11).
A webcast of Mr. Samant's presentations at the Noble Financial Group conference
will be available live and archived through the Events page in the Investors
section of the Vical website at www.vical.com. The Needham conference
presentation will not be webcast.

About Vical

Vical researches and develops biopharmaceutical products based on its patented
DNA delivery technologies for the prevention and treatment of serious or
life-threatening diseases. Potential applications of the company's DNA delivery
technology include DNA vaccines for infectious diseases or cancer, in which the
expressed protein is an immunogen; cancer immunotherapeutics, in which the
expressed protein is an immune system stimulant; and cardiovascular therapies,
in which the expressed protein is an angiogenic growth factor. The company is
developing certain infectious disease vaccines and cancer therapeutics
internally. In addition, the company collaborates with major pharmaceutical
companies and biotechnology companies that give it access to complementary
technologies or greater resources. These strategic partnerships provide the
company with mutually beneficial opportunities to expand its product pipeline
and address significant unmet medical needs. Additional information on Vical is
available at www.vical.com.

This press release contains forward-looking statements subject to risks and
uncertainties that could cause actual results to differ materially from those
projected. Forward-looking statements include statements about the company's
focus, collaborative partners, product candidates, and developmental status.
Risks and uncertainties include whether any product candidates will be shown to
be safe and efficacious in clinical trials, the timing of clinical trials,
whether Vical or its collaborative partners will seek or gain approval to market
any product candidates, the dependence of the company on its collaborative
partners, and additional risks set forth in the company's filings with the
Securities and Exchange Commission. These forward-looking statements represent
the company's judgment as of the date of this release. The company disclaims,
however, any intent or obligation to update these forward-looking statements.

The Vical Incorporated logo is available at
http://www.globenewswire.com/newsroom/prs/?pkgid=5768

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CONTACT: Vical Incorporated
Alan R. Engbring
(858) 646-1127
www.vical.com