REG-CLS Holdings PLC: Holding(s) in Company

TR1: notification of major interests in shares

1.Identity of the issuer or the underlying issuer of existing CLS Holdings Plc
shares to which voting rights are attached:

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights Yes

An acquisition or disposal of financial instruments which may result in No
the acquisition of shares already issued to which voting rights are
attached

An event changing the breakdown of voting rights No

Other (please specify):______________ No

3. Full name of person(s) subject to the notification F&C Asset
obligation: Management
plc

4. Full name of shareholder(s) (if different from 3.): See box 9
below

5. Date of the transaction (and date on which the threshold is
crossed or reached if different): 12 June 2009

6. Date on which issuer notified: 15 June 2009

7. Threshold(s) that is/are crossed or reached: 5%

8. Notified details:

A: Voting rights attached to shares

Class/type Situation previous to the Resulting situation after the
of shares Triggering transaction triggering transaction

if possible Number of Number of Number Number of voting % of voting
using the Shares Voting Rights of rights rights
ISIN CODE shares
Direct Indirect Direct Indirect

GB0001592475 2,428,458 2,428,458 1,964,978 - 1,964,978 - 4.09%

ORD GBP
£0.25

B: Financial Instruments

Resulting situation after the triggering transaction

Type of Expiration Exercise/ Number of voting rights that may % of
financial date Conversion be acquired if the instrument is voting
instrument Period/ Date exercised/ converted. rights

-

Total (A+B)

Number of voting rights % of voting rights

1,964,978 4.09%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

No significant holders

Proxy Voting:

10. Name of the proxy holder: F&C Asset Management plc

11. Number of voting rights proxy holder will cease to
hold:

12. Date on which proxy holder will cease to hold voting
rights:

13. Additional information:

14. Contact name: Peter Fraser, F&C Asset Management plc

15. Contact telephone number: 0131 718 1051

END