MGH and NEC Start On-Site Evaluation of NEC Cancer Diagnosis Assistance System e-Pathologist at MGH

Thu Oct 22, 2009 8:34am EDT

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TOKYO--(Business Wire)--
NEC Corporation (NEC; TSE: 6701) announced today it has started a joint
evaluation of NEC`s cancer diagnosis assistance system, e-Pathologist, at
Massachusetts General Hospital (Headquarters: Boston, MA, USA; President: Peter
L. Slavin, MD; MGH). 

The e-Pathologist system uses "machine intelligence" to detect tissue and cell
features and make quantitative measurements of key structures in digitized
images of slides of tissue sections stained conventionally with Hematoxylin &
Eosin (H&E) or subjected to immunohistochemistry reagents to assist pathologists
in making decisions that may contribute to the clinical management of cancer. 

With the advent of fast scanners that generate digital images of tissue slides,
the workflow of the pathology laboratory can be enhanced in a cost effective
manner by leveraging the advantages of digital images for both quantitative and
semi-quantitative analyses. As the number of cases and resulting tissue samples
requiring evaluation by pathologists increases, and the number of diagnostic
tests deployed for grading and other tests for cancer grows, the use of digital
pathology technologies, like the NEC e-Pathologist, become an important
component of improved patient care. 

NEC has been developing the e-Pathologist Cancer Diagnosis Assistance System
since 2003 by adapting its advanced image analysis, recognition and machine
learning technologies which were developed in NEC`s Central Research Laboratory
and its North American laboratory (NEC Laboratories America). In October 2008,
MGH and NEC entered into a collaboration to adapt modules of e-Pathologist to
meet clinical needs in the pathological diagnosis of breast and prostate
cancers. Sample slides were used to teach the e-Pathologist modules to capture
important image features linked to disease. The e-Pathologist modules being
installed at MGH target breast tissues and perform (1) detection of ROI (Region
Of Interest) based on features of potentially cancerous areas observed in H&E
stained slide images, and (2) selection and counting of target cells used in ER,
PR and Her-2 tests from specially stained slides. 

MGH scientists, with help from NEC researchers and engineers, will evaluate
e-Pathologist functions, and study an advanced pathology workflow in which the
e-Pathologist system is expected to have an important role in overall diagnostic

"MGH has long been a leader in medical innovations, and MGH Pathology has long
been committed to utilizing imaging and data analysis for diagnosis and
discovery. Digital pathology is obviously an important development in driving
such innovation. We are pleased to start the evaluation of the NEC e-Pathologist
system at our site," said Dr. David Louis, Chief of Pathology at MGH. 

"NEC is proud of working with MGH as a partner in the realization of core tools
for digital pathology," said Dr. Botaro Hirosaki, Senior Executive Vice
President and Member of the Board, NEC. "The integration of MGH`s pathology and
medical imaging know-how with NEC`s computer science and IT capabilities will
make important innovations to the pathology information field possible." 

MGH and NEC will also work together to adapt e-Pathologist for analyzing
prostate tissues. After on-site evaluation, NEC will continue to prepare the
e-Pathologist system for use in the clinic. 

About NEC Corporation

NEC Corporation is one of the world's leading providers of Internet, broadband
network and enterprise business solutions dedicated to meeting the specialized
needs of a diversified global base of customers. NEC delivers tailored solutions
in the key fields of computer, networking and electron devices, by integrating
its technical strengths in IT and Networks, and by providing advanced
semiconductor solutions through NEC Electronics Corporation. The NEC Group
employs more than 140,000 people worldwide. For additional information, please
visit the NEC website at: 

NEC is a registered trademark of NEC Corporation. All Rights Reserved. Other
product or service marks mentioned herein are the trademarks of their respective
owners. ©2009 NEC Corporation.

NEC Corporation
Chris Shimizu, +81-3-3798-6511

Copyright Business Wire 2009

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