Caliper Life Sciences and SRU Biosystems to Offer Label-free Services for Cell-based and Biochemical Assays

Caliper Discovery Alliances and Services division intends to expand its contract
services offering to include label-free assays from SRU Biosystems
WOBURN, Mass.--(Business Wire)--
SRU Biosystems today announced that Caliper Life Sciences will use SRU
Biosystems` label-free BIND® technology to offer new functional assays as part
of its Discovery Alliances and Services.

The label-free BIND technology, developed by SRU Biosystems, provides
researchers with a new ultra-high throughput screening and profiling system for
cell-based and biochemical assays. BIND technology for cell-based assays offers
an orthogonal screening tool to access new hits and lead molecules that are not
detected by other systems, including compounds that undergo G-protein switching,
non-G protein coupled pathways, inverse and partial agonists, and receptor
desensitization. The screening platform is robust and can be applied to both
over-expressed and endogenous receptors, and can be used with low numbers of
primary cells. The technology can also used for receptor profiling on native
cells, due to the high sensitivity of the response. Lastly, the BIND technology
provides a way to easily screen Gi-coupled GPCR targets and ion channels, which
have been traditionally difficult to assess.

"Caliper Life Sciences is an excellent partner for SRU. They are uniquely
positioned to offer BIND technology as a contract service to the biotechnology
and pharmaceutical communities. They have tremendous knowledge utilizing
innovative technologies to advance drug discovery and will provide an
outstanding new service to the drug discovery industry," said Rick Wagner,
Ph.D., President and CEO of SRU Biosystems.

SRU Biosystems` label-free BIND technology has extraordinary sensitivity and
application flexibility. It can be used for complex cellular assays such as GPCR
pathway analysis, ion channel assays and cell adhesion assays; as well as
biochemical assays, such as protein-protein binding, enzyme assays, and fragment
and small molecule screening. These applications have been utilized in exploring
assay development, 1536-well high throughput screening, and lead profiling. SRU
anticipates a continued expansion of its label-free BIND products, creating new
assay capabilities.

About Caliper Life Sciences

Caliper Life Sciences is a premier provider of cutting-edge technologies
enabling researchers in the life sciences industry to create life-saving and
enhancing medicines and diagnostic tests more quickly and efficiently. Caliper
is aggressively innovating new technology to bridge the gap between in vitro
assays and in vivo results and then translating those results into cures for
human disease. Caliper`s portfolio of offerings includes state-of-the-art
microfluidics, lab automation & liquid handling, optical imaging technologies,
and discovery & development outsourcing solutions. For more information please
visit www.caliperLS.com.

Caliper is a registered trademark of Caliper Life Sciences, Inc. and SRU BIND is
a trademark of SRU Biosystems, Inc.

About SRU Biosystems

SRU Biosystems, Inc., is a life science company offering novel, label-free tools
used to answer important biological questions in biomedical research and
pharmaceutical drug discovery. SRU`s label-free BIND® Technology can rapidly
analyze the interactions of genomic, peptide, antibody or small molecule
compound libraries against a wide range of cellular and biochemical targets.
www.srubiosystems.com

SRU Biosystems, Inc.
Brant Binder, +1-781-933-7255 x202
CFO
bbinder@srubiosystems.com
or
MacDougall Biomedical Communications
Jennifer Conrad, +1-781-235-3060

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