Avo Photonics and Case Western Reserve University Are Pleased to Announce the Completion of a Design and Development Contract for an Optical Coherence Tomography (OCT) Forward Imaging Catheter

HORSHAM, Pa.--(Business Wire)--
Nearly 4 million people nationwide suffer from cardiac arrhythmias each year,
according to the 2006 U.S. Cardiac Rhythm Management Market report by Frost and
Sullivan. About 2.5 million of these cases cannot be treated or controlled
through medication alone. Since pharmacological therapies have limited
effectiveness, radiofrequency (RF) catheter ablation has emerged as the
prominent approach for treating a broad range of arrhythmias. However, during
the procedure physicians have no direct visualization of intra-cardiac
structures, nor do they have a means to measure successful lesions.

Recognizing this problem, researchers at Case Western Reserve University began a
research program in 2008 to build an imaging catheter that would allow surgeons
to monitor treatment and visualize intra-cardiac structures. The researchers
selected Avo Photonics, Inc., of Horsham, PA, for a Phase 1 design contract. The
contract was awarded in September 2008. Avo`s rapid design effort provided a
pathway for a subsequent October 2008 award for the development of prototype
opto-mechanical systems. At the contract conclusion, Avo delivered eight forward
imaging catheters to the university.

The forward imaging catheters (FIC) built by Avo will be used as monitors during
RF cardiac arrhythmia therapy. These OCT catheters will lead to imaging
techniques that will improve the insertion and accuracy of RF catheters, thus
leading to better patient results and an expansion of approved FDA procedures
for cardiac arrhythmia therapy.

Case Western Reserve University`s lead investigator on the project is Dr. Andrew
Rollins, associate professor in the Department of Biomedical Engineering.
Christine Fleming, a graduate research assistant under the advisement of
Rollins, was instrumental in the design and development.

As a specialized opto-electronic engineering and manufacturing company, Avo
provided critical resources and experience to the program. The Avo team was led
by Program Manager Todd Rixman and Senior Optical Engineer Dr. David Demmer.
"Our extensive experience in fiber optic and medical products blended to create
reliable and elegant optical assemblies. We are pleased to be able to offer
these service to Case Western Reserve", stated Rixman.

In May of 2009, Case Western Reserve imaged heart tissue through the Avo
produced catheters, thus confirming Avo`s design and manufacturing expertise.
Both Dr. Rollins and Ms. Fleming expressed their gratitude to Avo Photonics.
"Avo provided excellent resources as the development process proceeded"
commented Dr. Rollins. "Avo`s attention to detail and resourcefulness allowed us
to move quite rapidly from concept to design to prototyping. We are looking
forward to continuing with the development efforts and providing the medical
community with this and other enhanced tools" continued Dr. Rollins.

This work was funded by under the Coulter-Case Translational Research
Partnership.

About Case Western Reserve University

Case Western Reserve University is among the nation's leading research
institutions. Founded in 1826 and shaped by the unique merger of the Case
Institute of Technology and Western Reserve University, Case Western Reserve is
distinguished by its strengths in education, research, service and experiential
learning. Located in Cleveland, Case Western Reserve offers nationally
recognized programs in the arts and sciences, dental medicine, engineering, law,
management, medicine, nursing and social sciences.

About Avo Photonics

Avo Photonics provides custom design and contract manufacturing services to
customers in the military, aerospace, medical, communications, and commercial
markets. Its unique pure service model assures Avo is focused on its customer's
products. From fundamental optical physics analysis, through mechanical,
electrical, thermal, and materials design for packaging/manufacturing, into
crafted prototypes and high volume production, Avo Photonics is a one-stop shop
for photonic packaging services.

For a complete overview of Avo Photonics` service offerings, visit
www.avophotonics.com or call 215-441-0107.

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Avo Photonics, Inc.
Neal Stoker, 215-441-0107 x109
marketing@avophotonics.com

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