U.S. Army Captain Michael Kelvington, commander of the Battle company, 1-508 Parachute Infantry battalion, 4th Brigade Combat Team, 82nd Airborne Division, bows next to remains of Gulam Dostager, a member of Afghan Local Police who was killed in the blast of an Improvised Explosive Device (IED) during the joint Tor Janda (Black Flag in Pashtu) operation, in Zahri district of Kandahar province, southern Afghanistan May 25, 2012.  REUTERS/Shamil Zhumatov  (AFGHANISTAN - Tags: MILITARY CIVIL UNREST CONFLICT TPX IMAGES OF THE DAY)

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Glenn Close has genes mapped

Actress Glenn Close (L) arrives at the 67th annual Golden Globe Awards in Beverly Hills, California January 17, 2010 file photo. REUTERS/Danny Moloshok

Actress Glenn Close (L) arrives at the 67th annual Golden Globe Awards in Beverly Hills, California January 17, 2010 file photo.

Credit: Reuters/Danny Moloshok

CHICAGO | Thu Mar 11, 2010 6:20pm EST

CHICAGO (Reuters) - Archbishop Desmond Tutu has done it. So has genome pioneer Craig Venter.

And now American film actress Glenn Close has joined a handful of celebrities to have their genome sequenced in the name of science.

Close, who stars in the FX television series "Damages" and is known for movie roles including "Fatal Attraction" and "Dangerous Liaisons," said the offer was too good to pass up.

"For me, anything that can move the science forward is worthwhile," Close said in a telephone interview. "It's pretty well publicized that I have mental health issues in my family."

Close, whose family illnesses include bipolar disorder and schizophrenia, is a founder of the nonprofit group BringChange2Mind, which raises awareness about mental illness.

New sequencing technologies through companies like Illumina of San Diego, which did Close's genome, have vastly reduced the cost of producing an entire map of the human genome -- essentially the genetic recipe that makes up an individual.

Whereas the first human genome cost $3 billion and took more than a decade to produce, Illumina charges $48,000 for the kind of sequencing Close got. The company would not say whether it charged her.

Scientists say even newer technology will bring the price down to $1,000 within five years, essentially less than the cost of an advanced type of X-ray called a CT scan.

Scientists hope having the entire genetic map of a person's DNA will begin to reveal the genetic causes of common diseases or determine a person's risk for genetic disease.

Eventually, they predict it will become a routine part of the medical record.

The offer to get her genome sequenced came not through her own connections as a celebrity, but those of her husband, David Shaw, the founder and former head of IDEXX Laboratories Inc, Close said.

"Jay Flatley, who is the head of Illumina, called me up," Close said. "He said there are very few named women who have gotten this done. I may be the first. I'm proud of that.

"In the future, I think it's going to be something that I think will be quite prevalent."

Close said she will sit down with a genetics counselor next month to get the results "and find out as much as I want to know."

But she said if there is something in her genome that is of scientific interest, she will consider making it public.

(Editing by Doina Chiacu)

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Comments (2)
Mikecimerian wrote:
Next to come: genetic profiling. Serving science or one’s vanity? Brave new world in deed.

Mar 11, 2010 9:31pm EST  --  Report as abuse
QUAD4 wrote:
QUAD4
WHAT REALLY TICKS ME OFF ABOUT THESE SO CALLED MOVIE STARS IS THAT THEY ALWAYS FIND SOMEWAY TO GET THEIR NAME IN NEWSPAPERS, INTERNET AND OTHER MEDIA.
$48,000 SHOULD HAVE WENT TO A CHARITY OR SOME MILITARY OUTFIT LIKE WOUNDED VET ORG.

Mar 13, 2010 5:45pm EST  --  Report as abuse
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