Zacks Analyst Blog Highlights: Isis Pharmaceuticals, Inc., GlaxoSmithKline, Bristol-Myers, Eli Lilly and Pfizer

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Tue Apr 6, 2010 5:00pm EDT

http://www.zacks.com/
CHICAGO--(Business Wire)--
Zacks.com announces the list of stocks featured in the Analyst Blog. Every day
the Zacks Equity Research analysts discuss the latest news and events impacting
stocks and the financial markets. Stocks recently featured in the blog include:
Isis Pharmaceuticals, Inc. (Nasdaq: ISIS), GlaxoSmithKline (NYSE: GSK),
Bristol-Myers (NYSE: BMY), Eli Lilly (NYSE: LLY) and Pfizer (NYSE: PFE). 

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the Pros newsletter: http://at.zacks.com/?id=4579

Here are highlights from Monday`s Analyst Blog:

Isis Inks Deal with Glaxo

Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) recently inked a major deal with
GlaxoSmithKline (NYSE: GSK) under which Isis ` antisense drug discovery platform
will be used for the development of new treatments for rare and serious
diseases, including infectious and ocular diseases. 

Isis will receive an upfront payment of $35 million under the deal which covers
up to six programs. In addition to the upfront payment, the company also stands
to receive up to $20 million in milestone payments for each program up to the
phase II proof-of-concept (PoC) stage. 

On completion of PoC studies, Glaxo has the option to license the compounds and
take over the development and commercialization of the compounds. If all six
programs are successful and commercialized to pre-determined sales targets, Isis
could receive almost $1.5 billion in license fees and milestone payments. 

Isis is also eligible to receive tiered double-digit royalties on sales of
products that are commercialized. 

This deal is a major boost for Isis. It not only validates the company`s
antisense technology, it also provides the company with funds in the form of
upfront, milestone and other payments. Meanwhile, this deal will allow Glaxo to
gain access to Isis` antisense technology which has the potential to be used for
the development of several therapeutic treatments. 

We are big fans of antisense technology which is the main area of focus at Isis.
We believe that antisense technology represents an exciting and potentially
revolutionary platform for developing therapeutic candidates to treat a wide
margin of diseases. 

Isis has several proprietary compounds in clinical development as well as
partnered programs with large pharmaceutical companies such as Bristol-Myers
(NYSE: BMY), Eli Lilly (NYSE: LLY) and Pfizer (NYSE: PFE). We currently have a
Neutral recommendation on the company. 

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