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Chocolate may cut cholesterol but only in some people: study

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Chocolates are pictured during the opening of the Nestle Chocolate Centre of Excellence in Broc near Fribourg in this September 7, 2009 file photo. REUTERS/Denis Balibouse

Chocolates are pictured during the opening of the Nestle Chocolate Centre of Excellence in Broc near Fribourg in this September 7, 2009 file photo.

Credit: Reuters/Denis Balibouse

NEW YORK | Tue Jun 1, 2010 9:02pm EDT

NEW YORK (Reuters Life!) - Eating chocolate could bring down cholesterol levels -- but only in small amounts and only in some people, according to an analysis of eight studies.

Dr. Rutai Hui of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing and colleagues found chocolate only helped people who already had risk factors for heart disease and only when consumed in modest amounts.

Eating moderate amounts of cocoa could be "a worthwhile dietary approach" for preventing high cholesterol in certain groups of people, the researchers concluded in a report in the American Journal of Clinical Nutrition (here).

The analysis came after several studies suggested that chocolate may be good for your health.

One study released in March showed that among 19,300 people, those who ate the most chocolate had lower blood pressure and were less likely to suffer a stroke or heart attack over the next 10 years.

But, like the new analysis, that research came with caveats; the difference in chocolate consumption between the top and bottom chocolate-consuming groups was around 6 grams, or about one-seventh of a Hershey's milk chocolate bar.

Hui and his colleagues searched the medical literature to find studies that looked at how cocoa affected blood fats, or lipids, and found eight trials including 215 people.

When all studies were analyzed together, the researchers found eating cocoa cut levels of LDL, or "bad" cholesterol, by about 6 mg/dL and reduced total cholesterol by the same amount.

But cocoa had no effect on cholesterol in the three highest-quality studies.

Further analysis showed that only people who ate small amounts of cocoa, an amount containing 260 milligrams of polyphenols or less, experienced cholesterol lowering effects. People who consumed more showed no effect. Polyphenols are antioxidant compounds found in fruits, vegetables, chocolate and red wine. A 1.25-ounce bar of milk chocolate contains about 300 milligrams of polyphenols.

The researchers also found that healthy people didn't get any cholesterol-lowering benefits from cocoa, but people with risk factors for heart disease, such as diabetes, saw their LDL cholesterol and total cholesterol drop by around 8 mg/dL each.

"Future research efforts should concentrate on higher-quality and more rigorous randomized trials with longer follow-ups to resolve the uncertainty regarding the clinical effectiveness," said Hui and his team.

"Then we can really eat chocolate without feeling guilty."

(Reporting by Reuters Health, Editing by Belinda Goldsmith)

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Comments (2)
StuartAnstis wrote:
If you want to know more about cholesterol and lowering cholesterol, check this site:
http://www.lipisite.com/high-cholesterol-diagnosis.html

Jun 03, 2010 2:02am EDT  --  Report as abuse
Philip123 wrote:
The Framingham study evidence underlying the “lipid hypothesis” was never strong to start with. Since then a massive cholesterol lowering campaign has shown no effect on heart disease rates. While an elegant and seemingly intuitive hypothesis, more and more openly people are rightly questioning the wisdom of the cholesterol lowering campaign.

Cholesterol is an essential component of every cell membrane and important for myriad physiologic functions. When Dr. Uffe Ravnskov, MD PhD looked at the medical literature he found something quite surprising had been documented there. On average people with higher cholesterol live longer.
http://healthjournalclub.blogspot.com/2009/10/do-people-with-high-cholesterol-live.html
and
http://healthjournalclub.blogspot.com/search/label/Cholesterol

This particular study which found a modest protective effect for chocolate in relation to cardiovascular disease found “cocoa had no effect on cholesterol in the three highest-quality studies.” and there was no dose response effect, i.e. a little chocolate lowered cholesterol more stopped lowering it, making an association with cholesterol even less likely. This study itself should also call into question the wisdom of a massive cholesterol lowering campaign.

Besides shouldn’t we be more focused on the effects of a drug or food on the actual disease then on some purported surrogate marker for the disease? I mean if it works to prevent the disease who cares about its effect on a possible blood marker for the disease.

Jun 03, 2010 6:38pm EDT  --  Report as abuse
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