UPDATE 1-Lilly diabetes drug as good as insulin in study

Tue Apr 16, 2013 9:40am EDT

* Drug proved as effective as long-acting insulin

* Drug also showed benefits when used with other treatments

April 16 (Reuters) - Eli Lilly & Co's experimental once-weekly diabetes drug dulaglutide proved as good as insulin in controlling blood sugar in type 2 diabetics in two late-stage studies, the company said on Tuesday.

The medicine met the studies' key goal of demonstrating non-inferiority to insulin glargine, a longer-acting form of insulin, in lowering hemoglobin A1c, a measure of controlling diabetes.

Further research showed dulaglutide demonstrated statistical superiority in lowering hemoglobin A1c compared to insulin glargine at one year in patients with type 2 diabetes who were already taking the diabetes drugs metformin and glimeperide, the company said.

Dulaglutide combined with insulin lispro, a fast-acting form of insulin, also was statistically superior in reducing hemoglobin A1c compared to insulin glargine in combination with insulin lispro at 26 weeks.

The company said it expects to submit data from the studies to U.S. regulatory authorities this year as it seeks marketing approval for the injectable medicine.

Last October, Eli Lilly released data showing dulaglutide lowered hemoglobin A1c levels more than twice-daily injections of Bristol-Myers Squibb Co's Byetta given for six months, oral metformin taken for 26 weeks, and Merck & Co's once-daily oral Januvia taken for one year.

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Comments (3)
eb2340 wrote:
We do not need worthless overpriced and dangerous drugs. We need congress to allow natural cures to flourish and stop suppressing such cures. We need to eliminate the strangelhold the drug industry has on this nation

Apr 16, 2013 11:47am EDT  --  Report as abuse
kidhustle wrote:
I think your Prius is double parking in front of the food co-op. You live in the greatest country in the world when it comes to advances in medicine–go ahead and have your baby in the bathtub and treat a fever with crushed up tree bark. I think I’ll put my trust in modern, tested, aproved medicine.

Apr 16, 2013 1:07pm EDT  --  Report as abuse
gsrao.aim wrote:
before few days fda reported

Incretin Mimetic Drugs for Type 2 Diabetes: Early Communication – Reports of Possible Increased Risk of Pancreatitis and Pre-cancerous Findings of the Pancreas

is dulaglutide is thoroughly observed for these adverse effects

Apr 16, 2013 9:10pm EDT  --  Report as abuse
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