Amgen melanoma drug shrinks tumors but fails secondary study goal
April 4 (Reuters) - Amgen Inc said its experimental drug to treat a deadly form of skin cancer shrank tumors, but did not significantly improve overall survival rates in patients enrolled in a late-stage study.
The most common serious adverse events observed in the trial include disease progression, a bacterial skin infection and fever, the company said.
Amgen said in June that data from the pivotal study showed that the drug improved survival by 21 percent for patients with advanced forms of melanoma compared with a standard white blood cell-boosting drug.
The company first reported in March last year that the drug, talimogene laherparepvec, met the study's main goal of inducing a durable response rate (DRR) - defined as a complete or partial tumor shrinkage lasting at least six months - in 16 percent of patients.
The company's shares were little changed at $123.87 in early trade on the Nasdaq on Friday. They closed at $124.13 on Thursday. (Reporting by Vrinda Manocha in Bangalore; Editing by Simon Jennings)
- Obama unveils U.S. immigration reform, setting up fight with Republicans |
- More arrests as protesters await Ferguson grand jury decision
- Western leaders step away from nuclear talks with Iran as deadline nears
- 'Immoral, but not illegal': metal warehousing games in the spotlight
- Exclusive: U.S. increasing non-lethal military aid to Ukraine