BRIEF-Glaxosmithkline says Phase III PETIT2 study meets primary endpoint

June 13 Fri Jun 13, 2014 2:48am EDT

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June 13 (Reuters) - Glaxosmithkline Plc

* GSK announces results of phase iii petit2 study of eltrombopag (promacta /revolade) in paediatric patients with chronic immune thrombocytopenia

* Efficacy results for petit2 were consistent across age cohorts

* Eltrombopag-marketed as promacta in u.s. And as revolade in europe and other countries across world-met its primary endpoint

* Study achievid a statistically significant improvement in platelet counts with almost 40 percent of patients treated with eltrombopag attaining a consistent platelet response for 6 of 8 weeks compared to placebo (39.7 percent versus. 3.4 percent, respectively, p<0.001).

* Most common adverse events (aes) occurring most frequently in eltrombopag arm included nasopharyngitis, rhinitis, cough and respiratory tract infection

* Serious aes were reported in 8 percent of eltrombopag-treated patients versus. 14 percent in placebo arm. Further company coverage:

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