Dec 6 U.S. health regulators on Friday approved
Auxilium Pharmaceuticals Inc's Xiaflex injections to
treat a condition that causes a painful curvature of the penis
called Peyronie's disease.
It marks the second U.S. approval for Xiaflex, which in 2010
received a Food and Drug Administration nod to treat Dupuytren's
contracture - a condition in which hardening of the connective
tissue collagen in the hands bends fingers toward the palm,
leaving a patient unable to straighten their hands or use their
Xiaflex is now the first FDA-approved non-surgical treatment
option for men with Peyronie's disease who have a plaque buildup
in the penis that results in a curvature deformity of at least
30 degrees upon erection, the agend.
The drug is injected directly into the collagen buildup to
break it down in order to help restore normal function to the
penis or hands.