UPDATE 3-MAP Pharma migraine drug hits all goals in study

* 792-patient trial involved inhaled drug Levadex

* No drug-related serious adverse events, company says

* Shares more than double

(Adds analyst comment, context, updates shares)

By Lewis Krauskopf

NEW YORK, May 26 (Reuters) - MAP Pharmaceuticals Inc (MAPP.O) said on Tuesday its experimental orally inhaled migraine drug reached all four goals of a late-stage clinical study, and its shares more than doubled.

The 150 percent rise in MAP shares marked the latest enormous stock jump for a small drug developer in the past two months, following leaps in Dendreon Corp (DNDN.O) and Vanda Pharmaceuticals Inc (VNDA.O).

MAP's drug, Levadex, showed statistical significance at two hours compared to placebo at relieving common symptoms of migraine: pain, nausea, and sensitivity to light and sound.

Levadex, formerly called MAP0004, also reached secondary measures of the 792-patient trial, including pain relief at 30 minutes and sustained relief for 48 hours.

The trial results are a major boost for MAP, whose shares tumbled some 75 percent in February on a failed study for its experimental pediatric asthma drug.

"It really was all we were hoping for," MAP Chief Executive Tim Nelson said in an interview regarding the Levadex data. "We think we really hit the requirements that the patients consistently articulate they want for this disorder."

MAP shares soared $4.73 to $7.88 in morning Nasdaq trading, after rising as high as $9.20. The shares traded at $11 in February, before the asthma drug setback.

Leerink Swann analyst Joseph Schwartz said expectations for the migraine study were low because it needed to hit four goals to succeed.

"Migraine is a tough area of drug development," Schwartz said. "These are outstanding results."

More than 29.5 million Americans suffer from migraines, an extremely painful often throbbing type of headache, according to the National Headache Foundation.

Levadex is an inhaled version of dihydroergotamine, an older drug used intravenously to treat migraines. Levadex is formulated to be used in MAP's proprietary inhaler, which is similar to a standard asthma inhaler except that patients breathe in to receive the drug rather than push on the device.