Nov 14 Endo Pharmaceuticals Holding Inc
said it discontinued development of its experimental
implant to treat abnormal growth of hands and feet caused by an
overproduction of growth hormone.
In February, the U.S. Food and Drug Administration had asked
Endo to conduct additional animal studies, including a
carcinogenicity study, before submitting a marketing application
for its octreotide implant.
Octreotide is a drug that inhibits the secretion of growth
Endo was testing the implant in a late-stage trial as a
treatment for acromegaly -- a condition caused by excessive
production of growth hormone.
Earlier this year, Endo stopped development of its
octreotide implant for the treatment of carcinoid syndrome, a
group of symptoms associated with a slow-growing type of tumor.
Endo shares closed at $33.01 on Friday on Nasdaq.