LONDON, April 15 A stem-cell repair technique
that has already been used to fix hundreds of injured race
horses is to be tested for the first time in people with damaged
Achilles tendons.
Privately owned British biotech firm MedCell Bioscience Ltd
said on Wednesday it would start clinical tests within 12 months
and planned to run a larger confirmatory study at several
European hospitals in 2011.
Patients will receive injections containing millions of
their own stem cells, which have been extracted and multiplied up
in a laboratory, and can regenerate new tissue to repair damaged
regions.
More than 1,500 race horses have been treated using the same
process and follow-up data suggests a 50 percent reduction in
re-injury over a three year period, compared with conventional
treatment.
"The move from clinical veterinary to human medicine is
inspiring and unusual -- we normally see the translation
happening the other way around," said Nicola Maffulli, an
orthopaedic surgeon and leading expert in sports medicine, who
will help conduct the trial.
Stem cell therapy has become the odds-on favourite for
tackling tendon damage in the world of horse racing, where
tendon damage to animals which can be worth millions of dollars
is all too common.
The repair technique was pioneered by surgeons at the Royal
Veterinary College north of London, who helped set up MedCell as
a spin-out company.
(Reporting by Ben Hirschler; Editing by David Holmes)