• Most Popular
  • Most Shared

UPDATE 1-Inspire Pharma nasal spray study fails to meet goal

Wed Apr 23, 2008 7:38am EDT

Stocks

   

(Adds details)

April 23 (Reuters) - Inspire Pharmaceuticals Inc (ISPH.O) said it will discontinue development of its epinastine nasal spray, after a late-stage trial to treat seasonal allergic rhinitis failed to meet the main goal.

The company said its analysis of the overall data in this program and the current competitive environment in allergic rhinitis indicate that epinastine nasal spray does not show potential to meet its desired product profile in the United States.

The 14-day trial, which included 798 patients, evaluated two concentrations of epinastine at two spray volumes, compared to placebo.

Both the epinastine treatment groups did not show statistical significance in treating rhinitis, compared to placebo.

The company said the drug was well-tolerated and there were no safety concerns in the trial.

Inspire acquired exclusive rights in 2006 from Boehringer Ingelheim International to develop and market epinastine nasal spray in the United States and Canada for the treatment of rhinitis. (Reporting by Jennifer Robin Raj in Bangalore; Editing by Anil D'Silva)



More from Reuters

No deaths, 40 injured in Jamaica airline crash

WASHINGTON (Reuters) - An American Airlines Boeing 737 overshot the runway while landing at the international airport in Kingston, Jamaica on Tuesday night, causing 40 injuries but no fatalities, a local newspaper reported.

» More Top News
Malaysians participate in computer attack and defence hacking competition during The 3rd Annual Hack-In-The-Box Security Conference 2004 in Kuala Lumpur on October 6, 2004. REUTERS/Bazuki Muhammad
Commentary:

Year of the breach

Data security breaches are nasty business and should be avoided at all costs, writes Kevin Prince, a chief technology officer at Perimeter e-Security. Here's a look at the biggest breaches and blunders of 2009.  Commentary 

Technology
A condominium under construction is seen in Miami, Florida October 15, 2007. REUTERS/Carlos Barria

Booming in the bust

For most Americans, the housing market collapsed about four years ago. For three real estate heavyweights, it's just getting started.  Full Article 

Housing Market