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Genzyme Corporation Updated Company Profile : Outlook, Strategy and Forecasts

Tue Jan 8, 2008 2:00am EST
NEW YORK--(Business Wire)--Reportlinker.com announces that a new market research report
related to the Pharmaceutical industry is available in its catalogue.

   Genzyme Corporation: Company Profile

   To order that report:

   www.reportlinker.com/p073698
/Genzyme-Corporation-Company-Profile.html

   (Due to its length, this URL may need to be copied/pasted into
your Internet browser's address field. Remove the extra space if one
exists.)

   For more information, contact Nicolas by email
nbo@reportlinker.com , by phone +33 4 37 65 17 03.

   This analysis examines the historical and forecast performance for
Genzyme in the ethical pharmaceutical sector. The profile encompasses
global company strategy, portfolio and pipeline analysis and
assessment of financial performance, with 1-6 year sales forecasts for
key drugs. An interactive forecasting and analysis tool provides
continually updated quantitative and qualitative information.

   Benchmark Genzyme's performance against key rivals in the ethical
pharmaceutical sector. Analyze how an anticipated increase in
competition for the Gaucher's treatment Cerezyme will drive
therapeutic diversification. Assess the company's steady expansion of
revenues generated via the oncology market

   CHAPTER 1 EXECUTIVE SUMMARY 2

   Key findings 2

   Historical and forecast ethical sales performance 3

   Therapeutic strategy 5

   Therapeutic strategy 5

   Launch and expiry outlook 8

   Externalization, geographic and molecule type strategies 11

   Externalization strategy 12

   Geographic strategy 13

   Molecule type strategy 13

   SWOT analysis 15

   Strengths 15

   Weaknesses 16

   Opportunities 17

   Threats 17

   CHAPTER 2 CORPORATE HISTORY 22

   Key findings 22

   Background 23

   Key corporate developments 24

   M&A history 25

   M&A history 25

   ILEX Oncology 26

   Bone Care International 26

   AnorMED acquisition 27

   Mozobil-the catalyst 27

   Bioenvision 28

   Current corporate structure 29

   Biotherapeutics 29

   Lysosomal storage disorders 30

   Genetics/diagnostics 31

   Current management team 32

   CHAPTER 3 HISTORICAL PERFORMANCE 33

   Key findings 33

   Introduction 34

   Revenue and growth rate analysis, 2001-06 34

   Revenue and growth rate vs. peer set 35

   Product analysis, 2001-06 39

   Product analysis, 2001-06 39

   Growth drivers 39

   Cerezyme 39

   Fabrazyme 40

   Renagel 40

   Synvisc 40

   Operating revenue and cost analysis, 2001-06 41

   Operating revenue/cost analysis 43

   CHAPTER 4 FORECAST PERFORMANCE 45

   Key findings 45

   Introduction 46

   Revenue and growth rate, 2006-12 46

   Product analysis, 2006-12 47

   Growth drivers 51

   Myozyme 51

   Renagel/Renvela 52

   Clolar 52

   Fabrazyme 52

   Synvisc 52

   Therapy area analysis, 2006-12 54

   Endocrine, metabolic and genetic disorders 57

   Cardiovascular & hematology 57

   Oncology 58

   Therapy area focus 59

   Launches and expiries analysis, 2006-12 62

   Launch portfolio 62

   Expiry portfolio 65

   Launch/core/expiry configuration 67

   Externalization analysis, 2006-12 70

   Geographic analysis, 2006-12 75

   Geographic analysis, 2006-12 75

   Molecule type analysis, 2006-12 79

   Molecule type analysis, 2006-12 79

   CHAPTER 5 KEY PRODUCTS AND COMPETITORS 84

   Key findings 84

   Overview 85

   Endocrine, metabolic & genetic disorders 86

   Cerezyme 86

   Overview 86

   Sales forecast 87

   Newsflow 87

   Competitive landscape 88

   Fabrazyme 91

   Overview 91

   Sales forecast 92

   Newsflow 92

   Competitive landscape 93

   Myozyme 95

   Overview 95

   Sales forecast 96

   Newsflow 96

   Competitive landscape 96

   Cardiovascular & hematology 99

   Renagel/Renvela 99

   Overview 99

   Sales forecast 100

   Newsflow 100

   Competitive landscape 101

   Oncology 104

   Clolar 104

   Overview 104

   Sales forecast 105

   Newsflow 105

   R&D pipeline 108

   CHAPTER 6 APPENDIX 109

   IMS vs. company-reported data reconciliation 109

   References 109

   Datamonitor Reports 109

   Abbreviations 110

   List of Tables

   Table 1: Genzyme Group Corporate Executive Committee 32

   Table 2: Peer set overview 35

   Table 3: Operating revenue/cost analysis ($m), 2001-06 41

   Table 4: Operating cost ratio analysis (% of total revenues),
2001-06 43

   Table 5: Product portfolio overview, sales ($m), 2006-12 48

   Table 6: Therapy area overview, sales ($m), 2006-12 54

   Table 7: Launch portfolio overview, sales ($m), 2006-12 62

   Table 8: Core portfolio overview, sales ($m), 2006-12 64

   Table 9: Expiry portfolio overview, sales ($m), 2006-12 65

   Table 10: Externally developed portfolio ($m), 2006-12 70

   Table 11: Molecule type overview, sales ($m), 2006-12 79

   Table 12: Key products overview 85

   Table 13: Cerezyme: overview 86

   Table 14: Cerezyme: sales forecast ($m), 2006-12 87

   Table 15: Cerezyme: newsflow 87

   Table 16: Fabrazyme: overview 91

   Table 17: Fabrazyme: sales forecast ($m), 2006-12 92

   Table 18: Fabrazyme: newsflow 92

   Table 19: Myozyme: overview 95

   Table 20: Myozyme: sales forecast ($m), 2006-12 96

   Table 21: Myozyme: newsflow 96

   Table 22: Renagel/Renvela: overview 99

   Table 23: Renagel/Renvela: sales forecast ($m), 2006-12 100

   Table 24: Renagel/Renvela: newsflow 100

   Table 25: Clolar: overview 104

   Table 26: Clolar: sales forecast ($m), 2006-12 105

   Table 27: Clolar: newsflow 105

   Table 28: Genzyme's R&D pipeline (Phase I-registration) 108

   List of Figures

   Figure 1: Historical and forecast ethical sales performance (%
CAGR), Genzyme and biotechnology peer set 3

   Figure 2: Therapeutic focus vs. biotechnology peer set (%), 2006 6

   Figure 3: Launch, core and expiry, absolute sales growth, 2006-12
(sales as % of 2006 sales), Genzyme 8

   Figure 4: Launch, core and expiry, absolute sales growth, 2006-12
(sales as % of 2006 sales), peer set 9

   Figure 5: Molecule type, externalization and geographic market
dependency (%) vs. peer set, 2006 11

   Figure 6: Molecule type, externalization and geographic market
dependency (%) vs. peer set, 2012 12

   Figure 7: SWOT analysis of Genzyme 15

   Figure 8: Genzyme timeline 24

   Figure 9: M&A/divestment history 25

   Figure 10: Current corporate structure 29

   Figure 11: Revenue & growth rate (ethical sales) ($m), 2001-06 34

   Figure 12: Ethical revenue ($m) and growth rate (%) vs. peer set,
2001-06 37

   Figure 13: Growth drivers/resistor products of historical revenue
performance ($m), 2001-06 39

   Figure 14: Operating revenue/cost analysis ($m), 2001-06 42

   Figure 15: Operating cost ratio analysis (% of total revenues),
2001-06 44

   Figure 16: Ethical revenue ($m) and growth rate (%), 2006-12 46

   Figure 17: Top five products by sales ($m), 2006 49

   Figure 18: Top five products by sales ($m), 2012 50

   Figure 19: Growth drivers and resistors by product, 2006-12 51

   Figure 20: Key strategic products, sales ($m), 2006-12 53

   Figure 21: Ethical sales by therapy area ($m), 2006-12 56

   Figure 22: Growth drivers and resistors by therapy area ($m),
2006-12 57

   Figure 23: Ethical sales by therapy area (%), 2006-12 59

   Figure 24: Therapy area focus compared with peer set (% total
ethical sales), 2006 60

   Figure 25: Therapy area focus compared with peer set (% total
ethical sales), 2012 61

   Figure 26: Launch schedule, sales ($m), 2006-12 63

   Figure 27: Core products sales growth ($m), 2006-12 65

   Figure 28: Expiry schedule, sales ($m), 2006-12 66

   Figure 29: Launch, core and expiry, sales ($m), 2006-12 67

   Figure 30: Launch, core and expiry, absolute sales growth, 2006-12
(sales as % of 2006 sales), Genzyme 68

   Figure 31: Launch, core and expiry, absolute sales growth, 2006-12
(sales as % of 2006 sales), peer set 69

   Figure 32: Externalization dependency, sales ($m), 2006-12 71

   Figure 33: Growth drivers and resistors, externally vs. internally
discovered products, sales ($m), 2006-12 72

   Figure 34: Externalization dependency vs. peer set, % total sales,
2006 73

   Figure 35: Externalization dependency vs. peer set, % total sales,
2012 74

   Figure 36: Geographical sales breakdown ($m), 2006-12 75

   Figure 37: Growth drivers and resistors by geography, sales ($m),
2006-12 76

   Figure 38: US dependency vs. peer set, % total sales, 2006 77

   Figure 39: US dependency vs. peer set, % total sales, 2012 78

   Figure 40: Growth drivers and resistors by molecule type, sales
($m), 2006-12 80

   Figure 41: Molecule type sales breakdown ($m), 2006-12 81

   Figure 42: Biologics dependency vs. peer set, % total sales, 2006
82

   Figure 43: Biologics dependency vs. peer set, % total sales, 2012
83

   To order that report:

   www.reportlinker.com/p073698
/Genzyme-Corporation-Company-Profile.html

   (Due to its length, this URL may need to be copied/pasted into
your Internet browser's address field. Remove the extra space if one
exists.)

   For more information, contact Nicolas by email
nbo@reportlinker.com , or by phone +33 4 37 65 17 03.

   More market research reports?

   Go to http://www.reportlinker.com

Reportlinker
Nicolas, +33 4 37 65 17 03
nbo@reportlinker.com

Copyright Business Wire 2008



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