Recession may mean less frequent Botox shots

LONDON (Reuters) - Recessionary pressures in the United States may mean some consumers opt to receive Botox injections less frequently but the maker of the anti-wrinkle treatment is confident users will not abandon the product.

Shares in U.S. drugmaker Allergan Inc (AGN.N) have been hit recently by concerns that the aesthetics market is slowing.

Chief Executive David Pyott said on Friday that Botox, which has an average treatment cost of around $400, would suffer less than more costly cosmetic procedures like breast implants.

"We'll see over time whether this pans out, but people might try and extend treatments a little bit," he said in an interview during a visit to London.

"That's more likely what I think would happen than people just saying 'I can't afford this, I'm just going to be ugly again'. That doesn't seem like an awfully appealing concept."

He added: "Botox is a very resilient brand."

In recent years, the average interval between Botox injections has declined to around 5-1/2 months from 6-7 months and Pyott said this figure might now creep up somewhat.

In contrast to most pharmaceuticals, cosmetic Botox is paid for out of pocket by consumers, making it more vulnerable to an economic downturn.

Allergan said after reporting quarterly results on January 30 that it had not yet seen an impact from the weakening economy on its business. Pyott declined to say on Friday whether this was still the case.

Sales of Botox, the company's biggest product, totaled $1.212 billion in 2007 and Allergan forecast in January it would sell between $1.365 billion and $1.415 billion this year.

Pyott said the market was still young and Botox, a toxin that temporarily paralyses nerves, had significant upside internationally. Allergan is also developing Botox for chronic daily headaches and as a treatment for overactive bladder.

Last year, sales of Botox for cosmetic purposes grew by 29 percent, while therapeutic use of the drug -- mainly for movement disorders and spasticity -- increased 19 percent.

"Therapeutic will start growing faster again, assuming headache and bladder get approved," Pyott said.

Allergan aims to present Phase III trial results on Botox in headaches at a June 4 research and development day in New York, assuming the data is ready in time. Pyott was cautious about the outcome, however, since proving the benefits of Botox in headache was "challenging".

Some doctors have already been using Botox on a so-called "off label" basis for headache, triggering a subpoena this month by the U.S. Department of Justice, which is investigating promotion of the product.

Pyott reiterated he was confident that Allergan had a complied with all the necessary rules, adding the investigation had not led to any change in its business practices.

U.S. doctors are free to prescribe drugs for uses not approved by the U.S. Food and Drug Administration but manufacturers are not allowed to promote them.

(Editing by Rory Channing and Mike Elliott)