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A boy cries as he recuperates after surgery during "Operation Smile" at a hospital in Manila's Makati financial district October 26, 2009. Operation Smile aim to provide free surgery for about a hundred children inflicted with cleft lips, cleft palates, and other facial deformities over a period of five days in Makati.  REUTERS/Cheryl Ravelo

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    FACTBOX: Tuberculosis around the world

    Thu Jul 3, 2008 8:10pm EDT

    (Reuters) - The Siberian region of Tomsk has nearly halved the number of people dying each year from tuberculosis (TB) since 1999 through a set of clear, simple steps.

    Health  |  Russia

    These steps, which a group of U.S. doctors called Partners in Health (PIH) helped impose, are now being exported around the world.

    The following are some facts on the Tomsk project and TB.

    * About a third of the world's population carries TB but only 5-10 percent of people with TB will become sick. Poor living conditions, diet and other illnesses turn the latent TB into an active illness.

    * Between 2000 and 2020 nearly 1 billion people will contract TB, the World Health Organisation (WHO) has said, from those 200 million will become ill and 35 million will die.

    * Lower and lower-middle income countries account for about 90 percent of the world's TB cases. The regions worst affected are Southeast Asia, Eastern Europe and sub-Saharan Africa.

    * In the Tomsk region of Russia, the number of deaths from TB per 100,000 people has dropped to 12.1 last year from 22.6 in 1999. This compares with a rise to 36.3 deaths per 100,000 people in the whole of Siberia from 28.6 in 1999.

    * Around 15 percent of new TB cases in Tomsk are drug-resistant. This is among the highest rates in the world: the average is just over 5 percent. Baku in Azerbaijan has the highest rate of drug resistance in new cases, at 22 percent.

    * The U.S. doctors who helped organize the project in the Tomsk region, Partners in Health, said they used the following drugs to treat patients with multiple drug-resistant tuberculosis:

    kanamycin, ofloxacin, ethionamide, Paser, cycloserine and pirazinamide. If the patient does not react to kanamycin, capreomycin replaces it.

    Sources: World Health Organisation (WHO) and Partners in Health (PIH)



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