• Most Popular
  • Most Shared

Gene discovery may help hunt for blindness cure

Tue Oct 7, 2008 3:24am EDT

Stocks

   

LONDON, Oct 7 (Reuters) - Scientists have discovered a gene mutation linked to the most common cause of blindness in the developed world, holding out the prospect of better treatments and perhaps eventually a cure.

British scientists said on Tuesday they had found six variants within the gene called Serping1 that were associated with age-related macular degeneration (AMD).

"Our findings add to the growing understanding of the genetics of age-related macular degeneration, which should ultimately lead to novel treatments for this common and devastating disease," Sarah Ennis and Andrew Lotery of the University of Southampton reported in the Lancet journal.

AMD -- which involves damage to the delicate cells of the macula, a region at the centre of the retina -- is increasingly common as people get older.

Around 90 percent of patients diagnosed with AMD have the so-called dry version, for which no treatment is currently available.

The rest have wet AMD, which occurs when tiny new blood vessels grow between the retina and the back of the eye. This form of the disease can be treated with modern drugs like Lucentis, from Novartis (NOVN.VX) and Genentech DNA.N, and Pfizer's (PFE.N) Macugen. (Reporting by Ben Hirschler; Editing by Dominic Evans



More from Reuters

Photo

Rajaratnam pleads innocent in Galleon case

NEW YORK (Reuters) - Galleon hedge fund founder Raj Rajaratnam and co-defendant Danielle Chiesi pleaded innocent on Monday to charges of securities fraud in what U.S. prosecutors describe as the biggest hedge fund insider trading case ever.

Demonstrators protest against the healthcare bill outside the Capitol in Washington December 15, 2009. REUTERS/Kevin Lamarque

Health bill passes crucial test

A sweeping U.S. healthcare reform bill appears headed for passage in the Senate after surviving a middle-of-the-night test vote.  Full Article | Video 

Two men shake hands in a file photo.    REUTERS/File

Let's make a deal

The battered M&A sector will make a tepid recovery in the coming year and three hot sectors will lead the way, according to a Thomson Reuters analysis.  Full Article