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Drug profits blow past Wall St estimates

NEW YORK
Thu Apr 19, 2007 1:04pm EDT

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A laboratory researcher in a file photo. Merck & Co., Schering-Plough Corp. and Wyeth all rode strong drug sales to quarterly profits that topped Wall Street expectations on Thursday, adding to the wave of good news for investors in major pharmaceutical companies. REUTERS/Sebastian Derungs

NEW YORK (Reuters) - Merck & Co. (MRK.N), Schering-Plough Corp. SGP.N and Wyeth WYE.N all rode strong drug sales to quarterly profits that topped Wall Street expectations on Thursday, adding to the wave of good news for investors in major pharmaceutical companies.

All three also had promising announcements on drugs in development moving closer toward potential approvals.

The encouraging financial results followed earnings that topped analysts' expectations from Johnson & Johnson (JNJ.N), Abbott Laboratories Inc. (ABT.N) and Eli Lilly and Co. (LLY.N) earlier this week.

"We thought the companies would beat expectations, but I didn't think they would beat by this degree," Deutsche Bank analyst Barbara Ryan said.

"Results across the board have been strong due to a number of factors," she said, including "solid underlying demand in the marketplace, new product introductions for Merck and continued strong demand for cholesterol-lowering drugs for Merck and Schering-Plough" as well as cost cutting.

Schering-Plough shares jumped more than 8 percent to $30.97. Merck shares were up just 12 cents to $49.80, but they climbed 4 percent last Thursday, when the company raised its first-quarter earnings forecast, and they are up more than 50 percent over the last 12 months, leading an across-the-board rally in the sector.

Wyeth shares were off under 1 percent to $55.85 on concerns of potential delays on drugs in late-stage development, analysts said.

Schering-Plough reported a 55 percent rise in first-quarter earnings, blowing past analysts' expectations by 13 cents per share as net profit rose to $543 million.

Sharply higher sales of the two cholesterol fighters sold in partnership with Merck -- Vytorin and Zetia -- and a 34-percent jump in overseas sales of the arthritis medicine Remicade helped fuel the impressive results.

Booming sales of newer medicines offset declines in Merck's older products as the company posted net earnings of $1.7 billion, or 78 cents per share, or 84 cents excluding restructuring charges.

Before Merck signaled its expected earnings to the market last week, analysts had on average been looking for a profit of 64 cents per share, according to Reuters Estimates.

Merck sales rose 7 percent to $5.8 billion, spurred by surging revenue from the co-marketed cholesterol drugs, new vaccines and the recently-launched Januvia diabetes treatment.

Older medicines, such as the antidepressant Effexor and the childhood vaccine Prevnar sparked Wyeth's strong quarter in which it posted a better-than-expected 12 percent profit rise.

The company earned $1.25 billion, or 92 cents per share, and excluding one-time items topped Wall Street estimates by 7 cents per share.

Positive pipeline news also highlighted the quarterly reports, adding to hopes that the impressive stock rally in the pharmaceutical sector may well have legs.

Merck said its migraine drug MK-0974 is now entering Phase III trials -- typically the final stage of testing before seeking approval of a new medicine.

Schering-Plough said late on Wednesday that it planned to begin two large late-stage studies of its promising experimental medicine to prevent dangerous blood clots in heart patients. The company has said SCH 530348 has the potential to be a multibillion-dollar medicine.

Wyeth said it still plans a third-quarter U.S. launch of Pristiq for the treatment of hot flashes, despite the need by regulators to review favorable data from new low-dose (50-milligram) trials that showed far less nausea and side effects than seen in earlier higher dose studies.

Wyeth also said the 50-mg dose of Pristiq was effective in separate trials against depression and better tolerated than higher doses. The company expects the FDA to decide by the first quarter of 2008 whether to approve Pristiq for depression, a potential slight delay over its prior forecast of late 2007 or early 2008. It said the FDA may require additional data from an osteoporosis drug in late stage development.



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