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The Russian Soyuz space capsule lands with Expedition 20 Commander Gennady Padalka of Russia, Flight Engineer Michael Barratt of the U.S. and Canadian circus billionaire Guy Laliberte in the vast steppe near the town of Arkalyk in northern Kazakhstan October 11, 2009. REUTERS/Yuri Kochetkov/Pool

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    Drug prevents bone loss in prostate cancer: Amgen

    CHICAGO
    Mon Jul 14, 2008 12:41pm EDT

    CHICAGO (Reuters) - Amgen Inc on Monday said that a trial of its experimental drug denosumab showed that it can prevent osteoporosis in men being treated with prostate cancer drugs that can cause bone loss.

    Science

    The three-year study of more than 1,400 men with non-metastatic prostate cancer undergoing androgen deprivation therapy showed denosumab produced greater increases in bone mineral density at the lumbar spine and non-vertebral sites than a placebo.

    Men receiving denosumab also experienced less than half the incidence of new vertebral fractures than those receiving the placebo, Amgen said.

    Both findings were statistically significant, it said.



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