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A boy cries as he recuperates after surgery during "Operation Smile" at a hospital in Manila's Makati financial district October 26, 2009. Operation Smile aim to provide free surgery for about a hundred children inflicted with cleft lips, cleft palates, and other facial deformities over a period of five days in Makati.  REUTERS/Cheryl Ravelo

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    FACTBOX-Mosquitoes spread deadly dengue fever across globe

    Wed Mar 12, 2008 7:58am EDT

    (Reuters) - Rapid urbanization has helped to fuel the spread of dengue fever to more than 100 countries, as the mosquitoes which carry the disease find fertile breeding grounds in cities.

    World  |  Science  |  Health

    Here are some facts about dengue, which poses a threat to 2.5 billion people, or two-fifths of the world's population, according to the World Health Organisation (WHO).

    WHAT:

    -- A severe, flu-like illness, caused by four distinct, but closely related, viruses known as Dengue 1, 2, 3 and 4.

    -- Known colloquially as bone-break fever for the severe muscle and joint pains it induces, the disease only causes death when it develops into a more severe form, dengue hemorrhagic fever (DHF).

    HOW:

    -- Virus-carrying female Aedes mosquitoes infect humans with the disease when they bite. It takes 4 to 7 days before a person shows symptoms of the disease.

    -- After incubating the virus for 8 to 10 days, the black and white striped mosquitoes can transmit it to susceptible individuals for the rest of their two-week life span.

    WHEN:

    -- Dawn and dusk are peak biting times for the silent, aggressive Aedes, whose name comes from the Greek for "unpleasant". Dengue can peak during rainy seasons when mosquito eggs hatch in stagnant water.

    WHERE:

    -- Tropical and subtropical regions. It is more common in urban areas where Aedes like to live.

    -- Southeast Asia and the Western Pacific are most seriously affected but dengue is now endemic in more than 100 countries around the world, including many in Africa, the Americas and the eastern Mediterranean.

    GLOBAL SPREAD:

    -- Urbanization provides conducive breeding and feeding conditions for dengue-carrying mosquitoes.

    -- The most important dengue mosquito is the predominantly urban species Aedes aegypti, which bites indoors in daytime and does not like to fly very far to find victims.

    -- Its eggs are laid in jars, pot plant dishes and containers where households store water, in buckets or pools of stagnant water on building sites, and in discarded car tires.

    INFECTIONS:

    -- The WHO says there may be 50 million cases of dengue worldwide each year of which 500,000 are treated in hospital for DHF, many of them children.

    -- About 22,000 people are estimated to have died of dengue last year, most of them children.

    TREATMENT:

    -- With no specific treatment for the four viruses, health officials focus on eradicating mosquitoes to prevent infections.

    Sources: Reuters, The World Health Organisation (here), Queensland Government (here) (Writing by Gillian Murdoch, Singapore Editorial Reference Unit; editing by Megan Goldin)



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