FACTBOX: Reaction to Bush "appeasement" remark

(Reuters) - President George W. Bush stirred up the campaign to replace him by suggesting on Thursday that Democratic presidential front-runner Barack Obama's pledge to talk to Iran's leader represented "the false comfort of appeasement."

Following is reaction to Bush's comments:

BARACK OBAMA, DEMOCRATIC PRESIDENTIAL CANDIDATE AND ILLINOIS SENATOR

"It is sad that President Bush would use a speech to the Knesset on the 6Oth anniversary of Israel's independence to launch a false political attack.

"It is time to turn the page on eight years of policies that have strengthened Iran and failed to secure America or our ally Israel. Instead of tough talk and no action, we need to do what Kennedy, Nixon and Reagan did and use all elements of American power -- including tough, principled, and direct diplomacy -- to pressure countries like Iran and Syria.

"George Bush knows that I have never supported engagement with terrorists, and the president's extraordinary politicization of foreign policy and the politics of fear do nothing to secure the American people or our stalwart ally, Israel."

JOHN MCCAIN, REPUBLICAN PRESIDENTIAL CANDIDATE AND ARIZONA SENATOR

McCain did not repeat the word "appeasement" but he criticized Obama's foreign policy approach of being willing to speak directly to U.S. foes. He singled out Iran, questioning why a U.S. president would want to talk to someone like Iranian president Mahmoud Ahmadinejad.

"It is a serious error on the part of Senator Obama. It shows naivete and inexperience and lack of judgment to say that he wants to sit down across the table from an individual who leads a country that says that Israel is a stinking corpse (and) that is dedicated to the extinction of the state of Israel. My question is, what does he want to talk about?"

HILLARY CLINTON, DEMOCRATIC PRESIDENTIAL CANDIDATE AND NEW YORK SENATOR

"President Bush's comparison of any Democrat to Nazi appeasers is both offensive and outrageous on the face of it, especially in light of his failures in foreign policy. This is the kind of statement that has no place in any presidential address and certainly to use an important moment like the 60th anniversary celebration of Israel to make a political point seems terribly misplaced.

"Unfortunately this is what we've come to expect from President Bush who has refused to change course in Iraq, neglected Afghanistan and failed to provide leadership on a range of important issues that face our country and the world."

JOSEPH LIEBERMAN, CONNECTICUT INDEPENDENT SENATOR

"President Bush got it exactly right today when he warned about the threat of Iran and its terrorist proxies like Hamas and Hezbollah. It is imperative that we reject the flawed and naive thinking that denies or dismisses the words of extremists and terrorists.

"It is critical to our national security that our commander in chief is able to distinguish between America's friends and America's enemies, and not confuse the two."

JOHN KERRY, MASSACHUSETTS DEMOCRATIC SENATOR