ZURICH Oct 8 Novartis AG's NOVN.VX cancer
drug Glivec had the potential to treat a rare heart and lung
condition in a mid-stage trial, but did not reach its main
target in the study.
Preliminary findings from the 59-patient study suggested
Glivec, known also by its generic name imatinib, provided a
treatment benefit in key measures used to monitor the
progression of the disease, pulmonary arterial hypertension
(PAH), Novartis said on Wednesday.
But Glivec did not reach statistical significance in its
main target in the study, which was improvement in the
six-minute walk test -- in which the patient tries to walk as
far as possible in six minutes -- Novartis said.
Swiss biotech Actelion ATLN.VX currently has the leading
drug for PAH, Tracleer, which rakes in more than $1 billion a
year but faces growing competition from drugs such as Gilead
Sciences Inc's (GILD.O) Letaris and Thelin from Pfizer Inc
Plans for further research into the potential of Glivec in
PAH will be announced at a later date, Novartis said.
(Reporting by Sam Cage; Editing by Hans Peters)