WASHINGTON, July 30 Pfizer Inc will pay
$490.9 million to resolve accusations of illegal marketing of
the drug Rapamune dating to Pfizer's 2009 acquisition of Wyeth
Pharmaceuticals Inc, the U.S. Justice Department said on
Wyeth trained its national Rapamune sales force to promote
the use of the drug in situations not approved by the U.S. Food
and Drug Administration (FDA), prosecutors said.
Pfizer disclosed the settlement on a preliminary basis in a
November 2012 securities filing. U.S. District Judge Vicki
Miles-LaGrange in Oklahoma City unsealed the final court papers
"Wyeth's conduct put profits ahead of the health and safety
of a highly vulnerable patient population dependent on
life-sustaining therapy," FDA Special Agent in Charge Antoinette
Henry said in a statement.
Rapamune was approved in 1999 for use in kidney transplants
to help keep the body's immune system from rejecting the new
organ, but prosecutors said Wyeth encouraged its sales force to
target all kinds of transplants.
The sales in question ended in July 2006, Pfizer said in a
"Pfizer was not a subject or target of this matter, and
cooperated fully with the government from the time it learned of
this investigation in October 2009," the company said.