FACTBOX: Cuba-U.S. feud since 1959

(Reuters) - Cuba and the United States have been feuding since Fidel Castro's 1959 Revolution.

Following are some highlights of Cuba-U.S. relations since 1959:

* January 1, 1959 - Cuban Revolution. Castro and his rebel army take power after flight from island of former dictator Fulgencio Batista, who had been backed by the United States.

* June 29, 1960 - United States suspends Cuban sugar import quota after Castro nationalizes Texaco refinery that refuses to process oil from Soviet Union.

* October 19, 1960 - United States begins partial economic embargo of Cuba.

* January 3, 1961 - Washington breaks diplomatic ties with Cuba.

* April 19, 1961 - Castro's troops defeat CIA-backed Cuban exile invasion force at Bay of Pigs.

* February 7, 1962 - Full U.S. trade embargo imposed on Cuba.

* October 1962 - Missile crisis. The presence of Soviet missiles in Cuba provokes standoff between Moscow and Washington. Many fear World War Three, but Russia decides to appease the United States and withdraws missiles.

* April-September 1980 - Mariel Boatlift. Cuba allows mass exodus of about 125,000 citizens to the United States, mostly via Mariel port west of Havana.

* August 1994 - Rafter Crisis. More than 30,000 Cubans flee island on flimsy boats, many perishing in shark-filled waters between Cuba and Florida. Washington and Havana sign migration accord to stem exodus and agree to a minimum of 20,000 legal entry visas per year for Cubans.

* January 21-25, 1998 - Pope John Paul II visits Cuba, condemning U.S. embargo but also calling for greater freedoms on the island.

* July 13, 2001 - U.S. President George W. Bush orders his administration to more strictly enforce sanctions in place against Cuba, and pledges increased support for pro-democracy forces on the island.

* November 2001 - Cuba purchases U.S. agricultural products as the two countries begin their first direct food trade since 1962 under an exception to embargo passed by U.S. congress.

* May 6, 2002 - In a speech entitled "Beyond the Axis of Evil," U.S. Undersecretary of State for Arms Control and International Security John Bolton accuses Cuba, along with Libya and Syria, of working to develop biological weapons, a charge Castro denies.

* December 8, 2003 - Bush creates commission to hasten a transition to democracy and assist a "Free Cuba." In May 2004, the commission recommends spending $80 million over two years on pro-democracy initiatives and broadcasts to Cuba.