FACTBOX: Radovan Karadzic appears in U.N. court

(Reuters) - Bosnian Serb wartime President Radovan Karadzic made his second appearance on Friday at the International Criminal Tribunal for the Former Yugoslavia (ICTY) to face charges of genocide in the 1992-95 Bosnian war.

The U.N. tribunal entered a plea of not guilty on his behalf after he refused to plead.

Here are facts about the court and some of its major cases:

THE COURT:

* The ICTY was set up by the U.N. Security Council in 1993.

* Based in The Hague, it was the first international body for the prosecution of war crimes since the Nuremberg and Tokyo trials held after World War Two.

* The tribunal has jurisdiction over individuals responsible for genocide, war crimes and crimes against humanity in the territory of the former Yugoslavia after January 1, 1991.

THE CASES:

* The tribunal has indicted 161 people. At present, 38 indicted war criminals are in custody in The Hague.

* There are 27 people on trial. Seventeen others are at various stages of proceedings and dozens of others have been passed to courts in Serbia, Bosnia, and Croatia.

Two people are at still at large -- Karadzic's military commander Ratko Mladic, also charged with the genocide of Bosnian Muslims, and Goran Hadzic, a Croatian Serb indicted for planning the murder and deportation of hundreds of non-Serbs in the self-declared Republic of Serbian Krajina in Croatia.

* Former Yugoslav President Slobodan Milosevic died in detention in March 2006, just months before a verdict was due in his four-year war crimes trial.

* Radislav Krstic, commander of the Bosnian Serb army's Drina Corps in 1995, was the first person convicted of genocide by the court, in August 2001. He was jailed for 46 years, but his sentence was later cut to 35, and the offence reduced to one of aiding and abetting genocide.

* Former Bosnian Serb army commander Vidoje Blagojevic was also found guilty, in 2005, of aiding and abetting genocide, and sentenced to 18 years.

* Milan Babic, ex-leader of the rebel Serbs in Croatia's Krajina region, was jailed for 13 years in 2004 for his role in the ethnic cleansing of almost 80,000 Croats in 1991. He was the first notable indictee to admit his guilt, and agreed to testify against Milosevic. He committed suicide in 2006.

* His fellow Krajina Serb leader, Milan Martic, was jailed for 35 years in 2007 for his role in the same expulsions.