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Abbott Laboratories Oral Hepatitis C Regimen Cure Rate High-Study-Reuters

Monday, 15 Oct 2012 01:27pm EDT 

Reuters reported that an all oral regimen of experimental hepatitis C medicines developed by Abbott Laboratories led to high cure rates in both new patients and those for whom prior treatment failed, according to initial results from a midstage study. After 12 weeks of treatment with three Abbott direct-acting antiviral medicines plus the older drug ribavirin, 99% of previously untreated patients and 93% of those who did not respond to older drugs achieved a sustained virologic response (SVR), which is considered cured, according to available data from a brief summary, or abstract, of the study. Abbott Laboratories will present much more detail on the Phase II study involving data from more patients at the American Association for the Study of Liver Diseases (AASLD) meeting in Boston. Based on the results, Abbott Laboratories said it would test its three drugs, each of which attacks the virus using a different approach, both with and without ribavirin in a large Phase III program aimed at gaining approval for the treatment.