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Bayer AG's Colorectal Cancer Treatment Stivarga Approved In Japan-DJ

Monday, 25 Mar 2013 04:26am EDT 

Dow Jones reported that Bayer AG said that Japan's Ministry of Health, Labor and Welfare has approved Stivarga tablets for the treatment of patients with unresectable, advanced/recurrent colorectal cancer. The approval is based on results from the pivotal Phase III CORRECT study that demonstrated an improvement in overall survival and progression-free survival compared to placebo in patients with metastatic CRC whose disease had progressed after approved standard therapies. Stivarga is an oral multi-kinase inhibitor that inhibits various kinases within the mechanisms involved in tumor growth and progression - angiogenesis, oncogenesis and maintenance of the tumor microenvironment. 

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