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Provider: Thomson Reuters Stock Report
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CytRx Corp completed phase 1b/2 progression-free survival and overall survival aldoxorubicin data in Second-Line Soft Tissue Sarcoma

Monday, 5 May 2014 06:00am EDT 

CytRx Corp:Presented updated progression-free survival (PFS) and overall survival (OS) results from its completed Phase 1b/2 clinical trial of aldoxorubicin in patients with advanced soft tissue sarcoma (STS).Data were presented as part of CytRx's Research and Development Day which took place on May 2 at Harvard Club in New York City.Data from Phase 1b/2 trial demonstrated that aldoxorubicin administered at its maximum tolerated dose (350mg/m(2)) showed substantial increase in median PFS in patients with advanced soft tissue sarcoma.Partial responses were observed in 5 of 13 patients (38 pct) and stable disease was observed in 6 of 13 patients (46 pct).Median PFS of 6.4 months was initially reported at ASCO and ESMO, in final reported data, observed median PFS had nearly doubled to 11 months, and median OS was 17 months. 

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