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GlaxoSmithKline Plc and Theravance Inc announces positive results from two phase III studies

Wednesday, 11 Jun 2014 07:30am EDT 

GlaxoSmithKline Plc and Theravance Inc:Positive results from two phase III studies, which showed that patients with chronic obstructive pulmonary disease (COPD) who received the anticholinergic, Incruse(tm) Ellipta (umeclidinium (UMEC) 62.5mcg), or umeclidinium 125mcg (an unlicensed dose).Says in addition to Relvar/Breo Ellipta an inhaled corticosteroid / long-acting beta2-agonist combination.Says achieved an additional improvement in lung function (FEV1) compared to patients receiving FF/VI plus placebo.Studies showed that for the primary endpoint of trough FEV1 at Day 85, the addition of UMEC 62.5mcg or UMEC 125mcg to FF/VI 100/25mcg resulted in a statistically improvement in lung function when compared with FF/VI 100/25mcg plus placebo in patients with COPD.