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EU Agency Rejects Sanofi SA's and Isis Pharmaceuticals Inc's Cholesterol Drug-Reuters

Friday, 14 Dec 2012 09:08am EST 

Reuters reported that European regulators have recommended against approval of Sanofi SA's and Isis Pharmaceutical Inc's drug Kynamro for treatment of a rare genetic disorder that causes unusually high cholesterol. The European Medicines Agency said it was concerned about the medicine‚Äôs safety, noting that a high proportion of patients stopped taking it within two years, mainly due to side effects such as flu-like symptoms, injection site reactions and liver toxicity. 

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