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Medicines Co Discontinues Phase 2b Trial of MDCO-2010

Thursday, 4 Oct 2012 05:30pm EDT 

Medicines Co announced that it has voluntarily discontinued its Phase 2b dose-ranging study of MDCO-2010, a serine protease inhibitor which was being developed to reduce blood loss during surgery. This action was taken in response to serious unexpected patient safety issues encountered during the trial, which had so far recruited 44 of a planned 90 patients in the first stage of the study. While the cause of the safety issues and any potential link to the study drug are still under investigation, the Company decided to end both the trial and further development of MDCO-2010 because of the evidence of risk to patients. The Company is conducting an in-depth assessment of all patient data from the study and any information related to drivers of risk. Once this evaluation is completed and reviewed with experts in the field, the findings will be published. 

Company Quote

0.01 +0.04%
11 Jul 2014