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Mirati Therapeutics Inc receives orphan drug designation from U.S. Food & Drug Administration for Mocetinostat in Myelodysplastic Syndrome

Tuesday, 17 Jun 2014 08:00am EDT 

Mirati Therapeutics Inc:Mocetinostat, company's spectrum selective HDAC inhibitor, has been granted Orphan Drug Designation by U.S. Food & Drug Administration as treatment for myelodysplastic syndrome (MDS).Mocetinostat is being developed in Phase 2 clinical studies in combination with Vidaza as treatment for intermediate and high-risk MDS, as well as single agent treatment in patients with diffuse large B-cell lymphoma (DLBCL).Says bladder cancer targeting specific genetic mutations in histone acetylation that increase the likelihood of response in tumor cells. 

Company Quote

-0.25 -1.31%
19 Dec 2014