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Veloxis Pharmaceuticals A/S' Final STRATO Clinical Study Data Demonstrates Potential For LCP-Tacro to Improve Tacrolimus-Induced Tremors


Monday, 20 May 2013 02:30am EDT 

Veloxis Pharmaceuticals A/S announced that data from the STRATO study demonstrates potential for LCP-Tacro to improve tacrolimus-induced tremors in stable kidney transplant patients. The study, Switching STudy of Kidney TRansplant PAtients with Tremor to LCP-TacrO (STRATO) clinical trial, was presented at the 13th American Transplant Congress, Abstract B1022, on May 19, 2013 in Seattle. In this open-label trial, 44 kidney transplant patients who were stable on twice-daily tacrolimus and had a complaint of hand tremor were switched to once-daily LCP-Tacro. Tremor was evaluated by independent neurologists using a validated rating scale (the FTM scale) and by an objective measurement of tremor frequency and amplitude by Tremorometer. In addition, the patients and the clinicians separately assessed global sense of improvement following the switch to LCP-TacroTM. Both the patient- and physician-reported global assessments demonstrated significant overall improvements following the switch to LCP-Tacro (p<0.001). Most patients in the study are continuing on a long-term extension phase of the study, receiving LCP-Tacro. Two other Veloxis-sponsored abstracts will be presented at the conference. 

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