Key Developments: Vical Inc (VICL.O)

VICL.O on Nasdaq

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28 Aug 2015
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Latest Key Developments (Source: Significant Developments)

Vical Inc reports top-line results from phase 1/2 trial of therapeutic genital herpes vaccine
Monday, 22 Jun 2015 04:11pm EDT 

Vical Inc:Says the primary endpoint of shedding rate was not met.Says both the monovalent and bivalent vaccines were generally well tolerated.Says are also moving our in-licensed antifungal compound toward a phase 1 trial initiation during the first half of 2016.Enrollment is complete in the phase 2 solid organ transplant trial;on track for data during the second half of 2016.Bivalent vaccine achieved statistically significant reductions in the rate of genital lesions.  Full Article

Vical Inc and AnGes MG announce collaboration to develop therapy for ebola virus disease
Wednesday, 14 Jan 2015 04:59am EST 

Vical Inc and AnGes MG:They have entered into collaboration.To develop and commercialize an equine polyclonal antibody therapy for patients afflicted with Ebola virus disease.No medicines or vaccines are currently approved for treatment of Ebola.  Full Article

Vical Inc granted six U.S. patents for HSV-2 vaccines
Wednesday, 8 Oct 2014 06:30am EDT 

Vical Inc:Announces issuance of six U.S. patents that provide broad coverage of DNA vaccines for herpes simplex virus type 2 (HSV-2), containing specific gene sequences and formulated with Vical's Vaxfectin adjuvant.These patents resulted from collaboration with laboratories of leading HSV experts David Koelle and Lawrence Corey at University of Washington under multi-year NIH grant.Intellectual property is jointly owned by the University of Washington and Vical.  Full Article

Vical Inc announces initiation of phase 1/2 trial of a therapeutic hsv-2 vaccine for genital herpes
Tuesday, 17 Dec 2013 07:00am EST 

Vical Inc:Says the initiation of its Phase 1/2 trial of the company's Vaxfectin-formulated therapeutic vaccine for herpes simplex virus type 2 (HSV-2), a cause of genital herpes, in about 156 subjects.Says the randomized, double-blind, placebo-controlled trial will evaluate safety, tolerability and efficacy in otherwise healthy HSV-2- infected patients aged 18 to 50 years at six key U.S. clinical sites.  Full Article

Astellas Pharma Inc's subsidiary and Vical Incorporated announce initiation of phase two trial of ASP0113
Tuesday, 10 Dec 2013 07:00am EST 

Astellas Pharma Inc and Vical Incorporated:Says Astellas Pharma Global Development, Inc., a subsidiary of company and vical initiaties a Phase two trial of ASP0113 in about 140 solid organ transplant (SOT) recipients.The global, randomized, double-blind, placebo-controlled trial is designed to evaluate the efficacy of ASP0113 compared to placebo as measured by the incidence of cytomegalovirus (CMV) viremia in CMV-seronegative subjects receiving a kidney from a CMV-seropositive donor.Says the study will also evaluate the safety of ASP0113 in this patient population.Says follow-up for each subject will continue for one year following enrollment.Says Astellas is conducting the trial under an exclusive worldwide license agreement with Vical to develop and commercialize ASP0113.Says Vical is providing development, regulatory and manufacturing support.  Full Article

Pomerantz Law Firm files class action against vical incorporated
Wednesday, 27 Nov 2013 05:01pm EST 

Vical Inc:Says Pomerantz Grossman Hufford Dahlstrom & Gross LLP files a class action lawsuit against the company and certain of its officers.Says the Complaint alleges that throughout the Class Period, the company made false and/or misleading statements, as well as failed to disclose material adverse facts about its business, operations, and prospects.  Full Article

Glancy Binkow & Goldberg LLP Announces Class Action Lawsuit Against Vical Incorporated
Tuesday, 12 Nov 2013 03:32pm EST 

Glancy Binkow & Goldberg LLP, representing investors of Vical Incorporated announced that a class action lawsuit has been filed in the United States District Court for the Southern District of California on behalf of a class (the "Class") comprising all purchasers of Vical securities between February 8, 2012 and August 9, 2013, inclusive (the "Class Period"). On August 12, 2013, Vical announced the results of the Phase 3 Allovectin trial, which showed that the vaccine failed to show an improvement over chemotherapy, and since "Allovectin simply did not provide the expected benefits," the Allovectin program would be terminated. The Complaint alleges that: The announcement of Allovectin's Phase 3 trial results was deliberately delayed to avoid revealing the truth to the market. Defendants lacked a reasonable basis for their positive statements about the Company and its outlook, including statements about its ability to launch Allovectin.  Full Article

Johnson & Weaver, LLP Files Class Action Suit Against Vical Incorporated
Friday, 1 Nov 2013 11:00am EDT 

Johnson & Weaver, LLP announced that a class action has been commenced in the United States District Court for the Southern District of California on behalf of purchasers of Vical Incorporated common stock during the period between February 8, 2012 and August 12, 2013 (the "Class Period"). The complaint alleges that Vical and certain of its officers and/or directors violated the Securities Exchange Act of 1934. Vical is a biopharmaceutical company that researches and develops products based on patented DNA delivery technologies for the prevention and treatment of serious and life-threatening illnesses, including cancer. All of Vical`s potential products are in the research and development stage, and no revenues have yet been generated from the sale of any products. Vical`s strongest candidate to receive approval by the U.S. Food and Drug Administration for eventual sale and marketing to consumers was Allovectin-7, an immunotherapy vaccine that targets cancer.  Full Article

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