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Vanda Pharmaceuticals Inc Announces Positive Phase III Results For Tasimelteon In Treatment Of Non-24-Hour Disorder


Tuesday, 18 Dec 2012 06:55am EST 

Vanda Pharmaceuticals Inc announced positive results from the SET (Safety and Efficacy of Tasimelteon) Phase III study, evaluating tasimelteon, a circadian regulator for the treatment of Non-24-Hour Disorder (Non-24). Tasimelteon succeeded in the primary endpoint of Entrainment of the melatonin (aMT6s) rhythm as compared to placebo. Additionally, tasimelteon demonstrated significant improvements across a number of sleep and wake parameters including measures of total sleep time, nap duration, and timing of sleep. Tasimelteon also showed significant improvements over placebo in the Non-24 Clinical Response Scale (N24CRS) as well as in the Clinical Global Impression of Change (CGI-C), an overall global functioning scale. These results provide robust evidence of a direct and clinically meaningful benefit to patients with Non-24. 

Company Quote

12.31
-0.53 -4.13%
20 Aug 2014