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Chiasma Inc (CXS.F)

CXS.F on Frankfurt Stock Exchange

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25 Jul 2016
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Summary

Name Age Since Current Position

David Stack

64 2014 Independent Chairman of the Board

Mark Leuchtenberger

51 2015 President, Chief Executive Officer, Director

Mark Fitzpatrick

52 2015 Chief Financial Officer, Treasurer, Secretary

Tara McCarthy

2016 Senior Vice President, General Counsel

Chaime Orlev

44 2011 Vice President, Finance and Administration

Steven Vickers

2016 Vice President - Sales

Roni Mamluk

48 2015 Chief Development Officer

John Thero

55 2015 Director

James Tobin

71 2015 Director

Todd Foley

43 2008 Independent Director

Ansbert Gadicke

57 2014 Independent Director

Bard Geesaman

2012 Independent Director

Scott Minick

63 Independent Director

John Scarlett

65 2015 Independent Director

Biographies

Name Description

David Stack

Mr. David (Dave) M. Stack is Independent Chairman of the Board of Chiasma, Inc. He has more than 25 years of industry experience in private companies. He is currently President, Chief Executive Officer and Chairman of Pacira Pharmaceuticals. He also remains a Managing Director at MPM Capital. From September 2001 to August 2004, he was President, Chief Executive Officer and a Director of The Medicines Company. Prior to that, he was the President and General Manager of Innovex. From 1993 to 1995, he was the Vice President of Business Development and Marketing for Immunomedics, and from 1992 to 1993, he served as the Director of Business Development and Planning for Infectious Disease, Oncology and Virology of Roche Laboratories where he was the Therapeutic World Leader of Infectious Disease. He held other commercial positions with Roche Laboratories for almost 11 years. Mr. Stack holds a degree in Pharmacy from Albany College, United States and a Bachelor of Science in Biology from Siena College, United States.

Mark Leuchtenberger

Mr. Mark W. Leuchtenberger is the President, Chief Executive Officer, and Director of Chiasma, Inc. since March 2015. Prior to joining us, Mr. Leuchtenberger was President and Chief Executive Officer and director of Acusphere, Inc. (OTCMKTS: ACUS), a biopharmaceutical company, or Acusphere, from September 2013 to January 2015. Prior to Acusphere, from March 2010 to February 2013, Mr. Leuchtenberger served as President, Chief Executive Officer and a director at Rib-X Pharmaceuticals, Inc. (now Melinta Therapeutics, Inc.), a biopharmaceutical company. Prior to that, from 2006 to 2009, Mr. Leuchtenberger served as President and Chief Executive Officer of Targanta Therapeutics Corporation, where he led the company’s initial public offering in 2007 and its acquisition in 2009. From 2002 to 2006, Mr. Leuchtenberger served as the President and Chief Executive Officer of Therion Biologics Corporation, or Therion. Prior to Therion, Mr. Leuchtenberger was a senior officer at Biogen Inc., where he led the late-stage development of Avonex and its launch in the United States and subsequently managed North American and international commercial operations. He is a director and past chairman of the Massachusetts Biotechnology Council Board of Directors, and currently serves as a trustee for Beth Israel Deaconess Medical Center and Chairman of the Advisory Committee for the MassDevelopment Emerging Technology Fund. He is a co-founder of Albor Biologics, Inc. and Alvos Therapeutics, Inc. Mr. Leuchtenberger received his M.B.A. from the Yale School of Management and his B.A. from Wake Forest University. He served as non-executive Chairman of the Board of Directors of Xenetic Biosciences, Inc. (OTCMKTS: XBIO), a biopharmaceutical company developing next-generation biologic drugs and novel oncology therapeutics, from May 2014 to April 2015.

Mark Fitzpatrick

Mr. Mark J. Fitzpatrick is Chief Financial Officer, Treasurer, Secretary of the company. since June 2015. Prior to joining us, he was Chief Financial Officer at Aegerion Pharmaceuticals, Inc. (NASDAQ: AEGR), a biopharmaceutical company specializing in the treatment of rare diseases, from May 2011 to June 2015. From July 2007 to April 2011, Mr. Fitzpatrick served as Chief Financial Officer of Proteon Therapeutics, Inc. (NASDAQ: PRTO), a biopharmaceutical company. He also held Chief Financial Officer positions at RenaMed Biologics, Inc., Dynogen Pharmaceuticals, Inc., WorldStreet Corporation, and Diacrin, Inc., and has more than 20 years of financial management experience in both public and private companies. Mr. Fitzpatrick received his B.S. in Accounting from Boston College in 1984 and earned a Certified Public Accountant certificate in the Commonwealth of Massachusetts in 1987.

Tara McCarthy

Ms. Tara McCarthy is Senior Vice President, General Counsel of the Company. She has joined Chiasma as Senior Vice President and General Counsel, responsible for legal strategy and compliance. Ms. McCarthy most recently served as the vice president of commercial law for Vertex Pharmaceuticals, building a global commercial legal team and helping to launch its INCIVEK ® , KALYDECO ® and ORKAMBI ® product lines in multiple countries, including the U.S. Prior to Vertex, she served as senior corporate counsel at Genzyme Corporation, where she was responsible for the company's Renal and Endocrinology business unit and its RENAGEL ® /RENVELA ® , HECTOROL ® and THYROGEN ® product lines. Before joining Genzyme, Ms. McCarthy served as assistant general counsel and director of investor relations for Health Dialog Services Corporation. She earned her J.D. from the University of Michigan Law School and a B.A. from the University of Massachusetts at Amherst.

Chaime Orlev

Mr. Chaime Orlev, CPA, is the Vice President, Finance and Administration of Chiasma, Inc. since December 2011. Mr. Orlev joined us in June 2010 as the Director of Finance. Prior to joining us, he was a financial consultant to several Israeli biotechnology and medical device companies from 2008 to 2010. From 2008 to 2009, Mr. Orlev served as Chief Financial Officer of Oramed Pharmaceuticals Inc. Mr. Orlev served as Chief Financial Officer of Gammacan International Inc. from 2005 to 2008 and as Vice President, Finance and Chief Financial Officer of Huntleigh from 2001 to 2004. Mr. Orlev received his M.B.A. from the Leon Recanati Graduate School of Business Administration at the Tel Aviv University and a B.A. in Business Administration from the College of Business in Israel. Mr. Orlev is a Certified Public Accountant under the laws of Israel.

Steven Vickers

Mr. Steven Vickers is Vice President - Sales of the Company. Mr. Vickers spent the past four years with Onyx Pharmaceuticals, which is now a subsidiary of Amgen. During this time, he served as senior national sales director for the company's hematology business, leading the successful launch of Onyx's KYPROLIS™ and BLINCYTO™ product lines. Prior to joining Onyx, Mr. Vickers served as a sales leader at Millennium Pharmaceuticals, Eisai Incorporated and Chiron Corporation. He earned his M.B.A. in Corporate Finance and Marketing from the University of Southern California and a B.S. from the University of California at Berkeley.

Roni Mamluk

Dr. Roni Mamluk, Ph.D., is the Chief Development Officer of Chiasma, Inc. Since March 2015. She served as our Chief Executive Officer from April 2013 to March 2015 and held various roles of increasing responsibility, including Chief Operating Officer and Vice President, Research and Development, from 2006 to April 2013. She also served as a member of our board of directors from April 2013 to March 2015. Since joining us, Dr. Mamluk has played a leading role in developing, and is one of the primary inventors of, our proprietary Transient Permeability Enhancer, or TPE, technology platform. She has also led the development of oral octreotide and ongoing improvements to our TPE platform. Dr. Mamluk joined us from Adnexus Therapeutics, Inc., where she established and led nonclinical research and development. Dr. Mamluk received her B.A. and Ph.D. from the Hebrew University. She also participated in a post-doctoral fellowship at Children’s Hospital/Harvard Medical School in the field of angiogenesis.

John Thero

Mr. John F. Thero, CPA is Director of the Company. Mr. Thero joined Amarin in November 2009 and has more than 20 years of senior financial and operational management experience, including more than 15 years supporting the growth of life science companies. Mr. Thero became President and CEO of Amarin in 2014 after previously serving as the company's President and initially as the company's Chief Financial Officer. Prior to Amarin, Mr. Thero was at ViaCell, Inc., where as Chief Financial Officer he helped guide the company to its successful sale to PerkinElmer, and Abiomed, Inc., where he held multiple positions, including Senior Vice President of Business Operations and Chief Financial Officer, and helped manage the company's transition from a development-stage company into a commercial entity. Mr. Thero began his professional career at Arthur Andersen LLP.

James Tobin

Mr. James R. Tobin is Director of the Company. Mr. Tobin, formerly president and CEO of Biogen, Inc. and Boston Scientific Corporation, will serve as a member of the Audit Committee. Mr. Tobin was most recently President and CEO of Boston Scientific Corporation from March 1999 to July 2009. Prior to Boston Scientific, he served as President and CEO of Biogen from February 1997 to December 1998, and President and COO of Biogen from February 1994 to February 1997. Prior to joining Biogen, Mr. Tobin was with Baxter International Inc., where he served as President and COO from 1992 to 1994, as Executive Vice President from 1988 to 1992, and in various management positions prior to 1988. Mr. Tobin served as lieutenant in the U.S. Navy from 1968 to 1972. He has been a Director of multiple private and public life science firms and hospitals, and currently serves on the boards of several private companies as well as Globus Medical, Inc. (NYSE:GMED) and Oxford Immunotec Global PLC (NASDAQ:OXFD). Mr. Tobin earned an M.B.A. from Harvard Business School and an A.B. from Harvard College.

Todd Foley

Mr. Todd Foley is a Independent Director of the company. Since May 2008. Mr. Foley is a Managing Partner at MPM Capital, where he has focused primarily on biotechnology investments. Mr. Foley joined MPM in 1999 and has been a partner since 2007. Prior to MPM, Mr. Foley’s career in the life science industry included positions in Business Development at Genentech, Inc., a biotechnology company and subsidiary of F. Hoffman-La Roche, and in management consulting with Arthur D. Little. Mr. Foley currently serves on the boards of various biotechnology and healthcare companies, including Valeritas, Inc., OSS Healthcare Inc., Iconic Therapeutics, Inc., Rhythm Holding Company, LLC, Clinical Ink, Inc., Semma Therapeutics, Inc. and Selexys Pharmaceuticals Corporation. He received his B.S. from the Massachusetts Institute of Technology, or MIT, and an M.B.A. from Harvard Business School. We believe Mr. Foley’s extensive business strategy and financial background and experience serving on the boards of several life science companies qualify him to serve on our board of directors.

Ansbert Gadicke

Dr. Ansbert K. Gadicke is Independent Director of the company. Since December 2014. Dr. Gadicke co-founded MPM’s venture investing activities in 1997. Prior to that, Dr. Gadicke led MPM’s Advisory and Investment Banking business from 1992 to 1996, and was in Boston Consulting Group’s Health Care Group from 1989 to 1992. He is a member of the board of directors of biotechnology companies, Mitobridge, Inc., OSS Healthcare, Inc., Radius Health, Inc. (NASDAQ:RDUS), Raze Therapeutics, Inc., Sideris Pharmaceuticals, Inc. and TriNetX, Inc. Dr. Gadicke has held research positions in biochemistry and molecular biology at the Whitehead Institute at MIT and the Biochemistry Department at Harvard University. Dr. Gadicke has been published in leading scientific journals such as Nature and Cell. Dr. Gadicke is also a member of the Board of Fellows of Harvard Medical School and the Research Advisory Council of Massachusetts General Hospital. Dr. Gadicke received his M.D. from J.W. Goethe University. We believe Dr. Gadicke’s extensive experience in the healthcare industry and in investment management qualify him to serve on our board.

Bard Geesaman

Dr. Bard J. Geesaman is Independent Director of the company. Since January 2012, Dr. Geesaman has served as a Managing Director at MPM. From 2012 to 2015, he was Executive Director, Life Sciences of the X PRIZE Foundation. He is the founder of Solasia Pharma K.K., a specialty pharmaceutical company that develops and commercializes oncology drugs. From 2003 to 2007 he served as the Vice President, Medical Development for Elixir Pharmaceuticals Inc., where he oversaw clinical strategy for drug development and the human genetics program, and was a member of the company’s business development team. Dr. Geesaman is a General Partner at F2 and F3 Ventures, two UK-based venture capital funds, and has served on their board of directors since 2004. Dr. Geesaman became board certified in Internal Medicine in 2000, after completing a Clinical Fellowship at the Massachusetts General Hospital. He received his Ph.D. from MIT, an M.D. from Harvard Medical School and a B.S. from University of California, Berkeley. We believe Dr. Geesaman’s managerial experience and extensive experience in the healthcare industry qualify him to serve on our board.

Scott Minick

Mr. Scott Minick is Independent Director of the company, He served as President and Chief Executive Officer of BIND Therapeutics, Inc. (NASDAQ: BIND), a biopharmaceutical company, or BIND. From 1998 to 2010, Mr. Minick was Managing Director of ARCH Venture Partners and was instrumental in the startup, development and financing of numerous ARCH portfolio companies, including BIND and Chiasma. From 1995 to 1998, Mr. Minick was Director, President and Chief Operating Officer of SEQUUS Pharmaceuticals, Inc. (NASDAQ:SEQU), a biopharmaceutical company that was acquired by ALZA Corporation. Mr. Minick was formerly an executive at Baxter International, Inc. and Eli Lilly & Company. He serves as a member of the board of directors of BIND and Alzheon, Inc., and is a trustee of Beth Israel Deaconess Medical Center. Mr. Minick received his postgraduate training in neurobiology at the Salk Institute, an M.B.A. from Northwestern University, and a B.A. from the University of California, San Diego. We believe Mr. Minick’s extensive knowledge of Chiasma’s business as a company director since October 2007 and extensive experience in the biopharmaceutical industry and as a venture capitalist and senior executive qualify him to serve on our board.

John Scarlett

Dr. John A. Scarlett is Independent Director of the company. Since February 2015. Dr. Scarlett has been Chief Executive Officer and director of Geron Corporation (NASDAQ: GERN), a biotechnology company, since September 2011 and President since January 2012. Previously, he was the President and Chief Executive Officer of Proteolix, Inc., a biotechnology company that merged with Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) in October 2009, and a founder and Chief Executive Officer of Tercica, Inc. (NASDAQ: TRCA), which was acquired by Ipsen S.A. in 2008. From 1993 to 2001, Dr. Scarlett was also the founder and Chief Executive Officer of Sensus Drug Development Corporation, which was acquired by Pharmacia Corporation in 2001, and co-founded Covance Biotechnology Services, Inc., a contract biologics manufacturing and process development business that was acquired by Akzo Nobel’s Diosynth Division in 2001. Earlier in his career, he worked for McNeil Pharmaceutical, a subsidiary of Johnson & Johnson, and Novo Nordisk Inc. He received his B.A. from Earlham College and his M.D. from the University of Chicago, Pritzker School of Medicine. He completed his training in Internal Medicine at the Hospital of the University of Pennsylvania and his fellowship in Endocrinology and Metabolism at the University of Colorado Health Sciences Center.