Profile: West Pharmaceutical Services Inc (WST)
11 Feb 2016
West Pharmaceutical Services, Inc. (West), incorporated on July 27, 1923, is a manufacturer of components and systems for the packaging and delivery of injectable drugs, as well as delivery system components for the pharmaceutical, healthcare and consumer products industries. The Company’s products include stoppers and seals for vials, prefillable syringe components and systems, components for intravenous and blood collection systems, safety and administration systems, advanced injection systems, and contract design and manufacturing services. The Company’s customers include producers of pharmaceuticals, biologics, medical devices and personal care products. The Company’s reportable segments include Pharmaceutical Packaging Systems segment (Packaging Systems) and the Pharmaceutical Delivery Systems segment (Delivery Systems).
Packaging Systems Segment
The Company’s Packaging Systems segment develops, manufactures and sells primary packaging components and systems for injectable drug delivery, including stoppers and seals for vials, closures and other components used in syringe, intravenous and blood collection systems, and prefillable syringe components. The Company has manufacturing facilities in North and South America, Europe and Asia Pacific, with affiliated companies in Mexico and Japan. Packaging Systems consists of three operating segments: Americas, Europe and Asia Pacific. Packaging Systems' products generally consist of elastomeric components offered in a variety of standard and customer-specific configurations and formulations, which are available with advanced barrier films and coatings to enhance their performance. West FluroTec barrier film is applied to reduce the risk of product loss by contamination and protect the shelf life of packaged drugs. The Company also applies a Teflon coating to the surface of stoppers and plungers to improve compatibility between the closure and the drug. B2-coating is a coating applied to the surface of stoppers and plungers using a process that eliminates the need for conventional silicone application. It helps manufacturers reduce product rejections due to trace levels of silicone molecules found in non-coated packaged drug compounds. FluroTec and B2-coating technologies are licensed from Daikyo.
The Company’s Westar RS and Westar RU post-manufacturing processes are documented and fully validated procedures for washing and siliconizing stoppers and syringe components to remove biological materials and endotoxins. The Westar RS process prepares components for introduction into the customer's sterilizer and the Westar RU process provides sterilized components. These processes increase the overall efficiency of injectable drug production by outsourcing component processing, thereby eliminating steps otherwise required in each of its customers' manufacturing processes, and help to assure compliance with the latest regulatory requirements for component preparation. The Company also offers Envision components that are inspected using automated vision inspection systems, ensuring that components (plungers and stoppers) meet enhanced quality specifications for visible and subvisible particulate and contamination.
The Company’s NovaPure components, which include serum and lyophilization stoppers and syringe plungers, incorporate quality by design principles and are manufactured utilizing advanced process technologies. The closures help to ensure the safety, efficacy and purity of injectable drug products. Its tamper-evident Flip-Off seals are sold in a range of sizes and colors to meet customers' needs for product identification and differentiation. The seals can be provided using printing for cautionary statements and embossing technology that can serve as a counterfeiting deterrence. As an adjunct to its Packaging Systems products, the Company offers contract analytical laboratory services for testing and evaluating primary drug-packaging components and their compatibility with the contained drug formulation. West Analytical Services provides the Company and its customers with in-depth knowledge and analysis of the interaction and compatibility of drug products with elastomer, glass and plastic packaging components. Its analytical laboratories also provide specialized testing for complete drug delivery systems.
Delivery Systems Segment
The Company’s Delivery Systems segment develops, manufactures and sells safety and administration systems, multi-component systems for drug administration and a range of custom contract-manufacturing solutions targeted to the healthcare and consumer-products industries. Delivery Systems has capability in product design and development, including in-house mold design and construction, an engineering center for developmental and prototype tooling, process design and validation and high-speed automated assemblies. In addition, Delivery Systems is responsible for the continued development and commercialization of the Company’s line of healthcare, administrative and advanced injection systems, including Daikyo CZ, SmartDose and other systems. Delivery Systems have manufacturing operations in North America and Europe.
Delivery Systems offers a range of products and services, such as it offers customer contract-manufacturing and assembly solutions, which use such technologies as multi-component molding, in-mold labeling, ultrasonic welding and clean room molding and device assembly used to manufacture customer-owned components and devices used in surgical, diagnostic, ophthalmic, other drug delivery systems, personal care and consumer products; the Company’s administration systems include sterile devices for the administration of drug products, including patented products such as the MixJect transfer device, the Mix2Vial needleless reconstitution system and vial adapters. The Company’s safety systems that are designed to prevent needle sticks are eris and NovaGuard SA for prefilled syringes and NovaGuard LP for luer lock syringes. The luer lock version of the Daikyo CZ syringe system was introduced, along with several sizes of sterile vials. CZ technology is licensed from Daikyo.
The Company’s SmartDose electronic patch injector system is under evaluation by several biopharmaceutical companies. This system is designed for controlled, subcutaneous delivery of high volume and high viscosity drugs, using prefilled Daikyo CZ cartridges. The system is fully programmable, has a single push-button operation and a hidden needle for safety. The ConfiDose auto-injector and SelfDose self-injection systems enhance patient compliance and safety. The needle remains automatically shielded at all times. These systems eliminate preparation steps and simplify the injection of drugs, providing patients with a sterile, single-use disposable system that can be readily used at home.
West Pharmaceutical Services Inc
101 Gordon Dr
PO Box 645
EXTON PA 19341-0645