Profile: Zimmer Holdings Inc (ZMH.N)
6 Dec 2013
Zimmer Holdings, Inc. (Zimmer), incorporated on January 12, 2001, designs, develops, manufactures and markets orthopaedic reconstructive, spinal and trauma devices, biologics, dental implants and related surgical products. The Company’s customers include orthopaedic surgeons, neurosurgeons, oral surgeons, dentists, hospitals, stocking distributors, healthcare dealers and, in their capacity as agents, healthcare purchasing organizations or buying groups. As of December 31, 2011, it had operations in more than 25 countries and market products in more than 100 countries and more than 100 manufacturing, distribution and warehousing and/or office facilities globally. It manages its operations through three geographic segments: the Americas, which is consisted of the United States and includes other North, Central and South American markets; Europe, which is consisted of Europe and includes the Middle East and Africa markets, and Asia Pacific, which is consisted of Japan and Australia and includes other Asian and Pacific markets. In November 2011, the Company acquired ExtraOrtho, Inc. (ExtraOrtho). In January 2012, the Company acquired Reno, Nevada-based Synvasive Technology, Inc. In May 2013, Zimmer Holdings Inc acquired Knee Creations LLC. In June 2013, Zimmer Holdings Inc acquired NORMED Medizin Technik GmbH.
The Company markets and sells products through three channels: direct to healthcare institutions, such as hospitals or direct channel accounts; through stocking distributors and healthcare dealers, and directly to dental practices and dental laboratories. Its products include orthopaedic reconstructive, spinal and trauma devices, biologics, dental implants and related surgical products.
Orthopaedic Reconstructive Implants
The Company offers a range of products for specialized knee procedures, including NexGen Complete Knee Solution, The NexGen CR product, The NexGen Legacy, Gender Solutions NexGen, The NexGen Revision Knee, Natural-Knee II System, Gender Solutions Natural-Knee Flex System, Innex Total Knee System, Zimmer Unicompartmental Knee Systems, Zimmer Patient Specific Instruments and Zimmer Segmental System.
NexGen Knee product line is a system for knee replacement surgery, which has application across the continuum of care in aspects of primary and revision knee arthroplasty, including cruciate retaining (CR), posterior stabilized (PS) and revision procedures. The NexGen Knee System offers joint stability, sizing and performance options in a unified system of interchangeable components, which can be tailored to an individual patient. TheNexGen Knee System provides surgeons with knee instrument options spanning multiple surgeon and treatment philosophies. The breadth and versatility of the NexGen Knee System allows surgeons to transition from one type of implant to another during surgery.
The NexGen CR product line is designed to be used in conjunction with a functioning posterior cruciate ligament. The NexGen CR-Flex Fixed Bearing Knee is designed to provide a range of motion for patients who require deep bending in their activities of daily living. The NexGen CR-Flex Femoral Components offer a tissue balancing (flexion balancing) solution, which allows the surgeon to adjust component sizing and balance and stabilize the implant without removing additional bone or wasting critical procedure time.
The NexGen Legacy Posterior Stabilized Knee product line provides stability in the absence of the posterior cruciate ligament. The PS capabilities can be augmented through the use of a NexGen LegacyPosterior Stabilized Flex (LPS-Flex) Knee. With its NexGen LPS-Flex Mobile Knee, it offers a mobile-bearing total knee treatment option in the United States market. Gender Solutions NexGen Femorals represent the knee implants shaped to offer fit and function optimized for the anatomical considerations. Gender Solutions Femorals are available in both NexGen CR-Flex and LPS-Flex configurations. The NexGen Revision Knee product line consists of different products, which are designed to provide clinical solutions to surgeons for revision situations, including multiple constraint levels for ligament and soft tissue inefficiencies and a bone augmentation implant system made from its Trabecular Metal Technology material.
The Company offers improved polyethylene performance in the NexGen Knee System with its conventional polyethylene and Prolong Highly Crosslinked Polyethylene, which offers wear and resistance to oxidation, pitting and cracking. The Natural-Knee II System consists of a range of interchangeable, anatomically designed implants which include CSTi Cancellous-Structured Titanium Porous Coating option for stable fixation in active patients. The Gender Solutions Natural-Knee Flex System adds its High Flex and Gender Solutions Knee design concepts to the Natural-Knee System. The Innex Knee System offers fixed bearing and mobile bearing knee components. The Innex Knee System is distributed in Europe and Asia Pacific.
The Zimmer Unicompartmental Knee System offers a flexion design for unicompartmental knee surgery. The system offers the surgeon the ability to conserve bone by replacing only the compartment of the knee, which has had degenerative changes. The Zimmer Patient Specific Instruments simplify a total or partial knee procedure and help appropriate placement of the final implant based on a surgeon’s preoperative surgical plan. Based on a patient’s magnetic resonance imaging (MRI) scan, a computer generated, custom guide is produced to conform to a patient’s knee anatomy.
The Zimmer Segmental System is a system designed to address patients with bone loss associated with disease, trauma or revision. Its hip replacement products include Zimmer M/L Taper Hip Prosthesis, Zimmer M/L Taper Hip Prosthesis with Kinectiv Technology, Alloclassic (Zweymuller) Hip System, CLS Spotorno Hip System, CLS Brevius Hip Stem with Kinectiv Technology, Fitmore Hip Stem, Continuum Acetabular System, Trilogy IT Acetabular System, Allofit IT Alloclassic Acetabular System, Maxera Cup and Trabecular Metal Modular Acetabular System. The Zimmer M/L Taper Hip Prosthesis offers a proximally porous-coated wedge-shaped design. The Zimmer M/L Taper withKinectiv Technology is a system of modular stem and neck components designed to help the surgeon restore the natural hip joint center intraoperatively by addressing the variables of leg length, offset and version independently.
Alloclassic (Zweymuller) Hip System is a cementless hip system. The CLS Spotorno Stem is a hip prostheses. In addition to the product line provide the capability for restoration of the physiological center of rotation. The Fitmore Hip Stem offers the surgeon a short, bone preserving stem. Continuum Acetabular System, Trilogy IT Acetabular System and Allofit IT Alloclassic Acetabular System offer the surgeon a choice of bearing options to meet the clinical and lifestyle needs of each patient. Bearing options include Longevity Highly Crosslinked Polyethylene, Metasul Metal-on-Metal Technology and a BIOLOX delta Ceramic-on-Ceramic Technology (where Zimmer has regulatory clearances). The Maxera Cup provides a head, ceramic-on-ceramic option for the younger and more active patient. The Maxera Cup presents orthopaedic surgeons with a system, which offers a range of motion and a bearing to enable the restoration of a patient’s active lifestyle. The Trabecular Metal Modular Acetabular System incorporates fixation surface of Trabecular Metal Material. In addition, it offers aTrabecular Metal Acetabular Revision System, which provides the surgeon with a range of off-the-shelf options to address a range of bone deficiencies encountered during acetabular revisions.
The Company’s portfolio, shoulder and elbow products, is designed to treat arthritic conditions, soft tissue injuries and fractures. Its products include Bigliani/Flatow Complete Shoulder Solution Family, Trabecular Metal Glenoid, Trabecular Metal Reverse Shoulder System, Zimmer Anatomical Shoulder System and Coonrad/Morrey Total Elbow. The Trabecular Metal Glenoid offers surgeons a glenoid component. The Trabecular Metal Reverse Shoulder System incorporates materials and offer biological ingrowth potential through the utilization of Trabecular Metal Technology. Zimmer Anatomical Shoulder System can be adjusted to each patient’s individual anatomy. This portfolio of products includes the Anatomical ShoulderInverse/Reverse System, and the Anatomical Shoulder Fracture System. The Coonrad/Morrey Total Elbow product line is a family of elbow replacement implant products to address patients with conditions of severe arthritis or trauma.
The Company’s dental products division manufactures and/or distributes dental reconstructive implants, for individuals who are totally without teeth or are missing one or more teeth; dental restorative products, aimed at providing a more natural restoration to resemble the original teeth, and dental regenerative products, for soft tissue and bone rehabilitation. Its dental reconstructive implant products and surgical and restorative techniques include Tapered Screw-Vent Implant System, AdVent Implant System and Tapered SwissPlus Implant System. Tapered Screw-Vent Implant System provides the clinician a tapered geometry, which resembles the natural shape of a tooth root. The AdVent Implant System is a transgingival, one stage design, which utilizes the same surgical system as the Tapered Screw-Vent Implant System. The Tapered SwissPlus Implant System incorporates multiple lead threads and a tapered body to allow it to be placed in tight interdental spaces. The Tapered SwissPlus Implant System also incorporates an internal connection.
The Company offers a range of prosthetic devices, as well as a custom solution, such as Zimmer Hex-Lock Contour Abutment and Restorative Products, and its Hex-Lock Short Abutment and Restorative System. Its contour lines feature prepared margins, titanium and ceramic options and snap-on impression caps. Its Hex-Lock Short Abutment and Restorative System is an all-inclusive solution, which promotes posterior restorations. It also offers the Zimmer Contour Zirconia Abutment.
The Company’s Puros biologic offering is an allograft material, which in the case of mineralized bone and dermal tissues provides bone and soft tissue grafting material for use in oral surgery. Zimmer Dental offers a range of distinct Puros Allograft products to use together or separately for bone and soft tissue grafting needs. It distributes the Puros Allograft Products through an agreement with RTI Biologics, Inc. Through this same agreement with RTI Biologics, Inc., it provides CopiOs Pericardium Membrane in the United States Sourced from bovine pericardial tissue, the CopiOs Pericardium Membrane provides the characteristics of natural tissue and can be used as a direct substitute for Puros Pericardium Membranes.
The Company’s Spine products division designs, manufactures and distributes medical devices and surgical instruments. It provides surgeons a range of technologies for posterior and anterior procedures in the cervical, thoracic and lumbar regions of the spine. Zimmer Spine’s portfolio of spinal solutions includes PathFinder NXT Minimally Invasive Pedicle Screw System, Zimmer Universal Clamp Spinal Fixation System, Sequoia Pedicle Screw System, Ardis Interbody System, Trinica Select Anterior Cervical Plating System, Biological Products, Dynesys Dynamic Stabilization System and Wallis Posterior Dynamic Stabilization System (available outside the United States only).
The PathFinder NXT System builds on the legacy of the PathFinder Device. The Pathfinder NXT System is designed to allow for a mini-open or true percutaneous approach. Zimmer Universal Clamp Spinal Fixation System used alongside traditional hooks, screws and wires to treat scoliotic deformities and correct complex spinal pathologies. The Ardis Implant features a self-distracting nose, convex geometry and range of sizes. This versatile PEEK-OPTIMA Device incorporates a space for graft placement, plus an advanced tooth design to resist migration and expulsion during procedures. Trinica Select Anterior Cervical Plating System provides visual confirmation of screw capture, as well as a range of screw options to customize the construct depending on patient need.
Zimmer Spine offers a range of bone void filler products to accommodate surgical procedures. Puros Demineralized Bone Matrix is in Putty and Putty with Chips formulations, and the CopiOs Bone Void Filler family of products includes synthetic bone graft material in the form of sponges or pastes, which are used to fill bone voids during spine surgery. The Dynesys Dynamic Stabilization System is indicated for use as an adjunct to fusion in the United States. Wallis Posterior Dynamic Stabilization System is a spinal implant, which was designed to stabilize the lumbar spine while preserving the anatomy and minimizing the need for bony resection. The Wallis System combines a PEEK-OPTIMA Spacer linked to the vertebrae through a polyester band, which permits an even distribution of stresses on bone.
Zimmer Trauma offers a range of products, including Zimmer Natural Nail System, NCB Polyaxial Locking Plate System, Zimmer Periarticular Locking Plate System, Zimmer Universal Locking System and Zimmer Cable-Ready System. The Zimmer Natural Nail System includes a series of intramedullary nails designed to address a range of long bone fractures. The nails are anatomically shaped and incorporate a feature, which allows the screws to be linked to the nails. NCB Polyaxial Locking Plates provide surgeons with the ability to place screws with polyaxial freedom and utilize both conventional and locking technology in the treatment of complex fractures of the distal femur, proximal humerus and proximal tibia.
The Zimmer Universal Locking System is a system of mini and small fragment plates, screws and instruments for fracture fixation. The Universal Locking System plates resemble standard plates, which allow the plates to be used as compression plates, locked internal fixators or as an internal fixation system combining both techniques. The Zimmer Cable-Ready System includes a series of instruments, cables and other implants, which help a surgeon treat different fracture types, including those, which occur around a previously implanted device (periprosthetic). The cables are wrapped around the bone and then secured, either to themselves or to plates, to provide fixation for fractured limbs.
The Company develops, manufactures and markets products, which support reconstructive, trauma, spine and dental implant procedures. The Surgical product portfolio includes PALACOS Bone Cement, Hi-Fatigue Bone Cement, A.T.S. Automatic Tourniquet Systems, Pulsavac Plus, Zimmer Blood Reinfusion System (ZBRS) and Hemovac Blood Management System.
The Company has the United States and Canada distribution rights for the PALACOS line of bone cement products manufactured by Heraeus Kulzer GmbH. Included in these brands are PALACOS R and PALACOS R+G Bone Cements, as well as PALACOS LV and PALACOS LV+G Bone Cements. The PALACOS R+G and PALACOS LV+G products are bone cements with the antibiotic gentamicin pre-mixed in the formulation. The Company has European and Asian distribution rights for the Hi-Fatigue line of bone cement products manufactured by aap Biomaterials GmbH & Co. KG. Included in these brands are Hi-Fatigue and Hi-Fatigue G Bone Cements. The Hi-Fatigue G Bone Cement utilizes the antibiotic gentamicin pre-mixed in the formulation.
The A.T.S. Tourniquet Systems Product Line is the Company’s family of tourniquet machines and cuffs, which are designed to create a bloodless surgical field. The portfolio includes the A.T.S. 3000 Tourniquet System, which utilizes technology to determine the patient’s appropriate Limb Occlusion Pressure (LOP) based on the patient’s specific physiology. The Pulsavac Systems are used for cleaning and debridement of contaminants and foreign matter from wounds using simultaneous irrigation and suction. All three Pulsavac Systems are disposable to reduce the risk of cross contamination. While Pulsavac Plus and Pulsavac Plus LP Wound Debridement Systems are both battery-powered, the Pulsavac Plus AC Wound Debridement System is a disposable system, which is powered by a reusable alternate current (AC) power source. Zimmer Blood Reinfusion System (ZBRS) and Hemovac Blood Management System supports the clinician in managing patient blood loss after a surgical procedure. The ZBRS product is a closed-loop postoperative system.
The Company competes with Johnson & Johnson, Stryker Corporation, Biomet, Inc., Smith & Nephew plc, Wright Medical Group, Inc., Synthes, Inc., Tornier, Inc., B. Braun, Waldemar LINK GmbH & Co., KG, Mathys AG, Nobel Biocare Holding AG, Straumann Holding AG, Dentsply International and Biomet, Inc.
Zimmer Holdings Inc
345 East Main Street
WARSAW IN 46580