Reuters - Video

EDITION: U.S. | U.K. | IN

Technology

New computer software to unravel embryonic development cell by cell

Wednesday, August 06, 2014 - 02:51

Researchers at the Howard Hughes Medical Institute Janelia Research campus are using a new type of computer software to track and image how a nervous system develops in unprecedented detail. The new system is able to track individual cells during embryonic development, giving scientists a powerful to tool to create a blueprint of how brains form. Ben Gruber reports.

▲ Hide Transcript

View Transcript

INTRO: Researchers at the Howard Hughes Medical Institute Janelia Research campus are using a new type of computer software to track and image how a nervous system develops in unprecedented detail. The new system is able to track individual cells during embryonic development, giving scientists a powerful to tool to create a blueprint of how brains form. Ben Gruber reports. STORY: This is the first stage of brain development in a fruit fly embryo. It's an unprecedented view -- every single dot represents a single cell. Phillip Keller and his fellow researchers at the Janelia Research Campus in Virginia are tracking each of them as they organize into a working brain. (SOUNDBITE) (ENGLISH) JANELIA RESEARCH CAMPUS GROUP LEADER PHILLIP KELLER SAYING: "We basically want to understand how development happens. What are the fundamental principles that rule the mechanisms of development? How do you actually get from one cell to a complex multicellular organism in a very robust manner?" Answers to those questions have always eluded scientists. But now, thanks to new computer software that can process massive amounts of data in near real time, mapping how cells form into a complex nervous system is possible. A couple of years ago Keller and his group developed the simultaneous multi-view light sheet microscope which captures three-dimensional images of cells with unprecedented speed and precision over a period of days. But organizing what amounted to terabytes worth of data into visualizations the scientists could study took weeks. The new software can do it in a matter of minutes. Researcher Fernando Amat says the team have also developed a colour system that allows them to track individual cells during brain development. (SOUNDBITE) (ENGLISH) JANELIA RESEARCH CAMPUS BIOFORMATICS SPECIALIST FERNANDO AMAT SAYING: "We assign a color, a random color, to each cell at the beginning and then we propagate these colors based on the tracking information. So, what you can see is basically how each single-cell as they divide they go to different parts of the organism. And so, they become kind of colour clusters, so you see basically how each, let's say, tissue or part of the embryo where it came from. What's the original cell that it came from." And by following the paths of these cells, the scientists hope create how blueprint of how brains form. Keller says that the researchers are currently using the technology to study development in fruit flies and zebrafish. But he says even though these organisms are simple compared to the complex development of human nervous systems, there is still a lot to be learned. (SOUNDBITE) (ENGLISH) JANELIA RESEARCH CAMPUS GROUP LEADER PHILLIP KELLER SAYING: "If you compare the anatomy of a brain in a zebra fish to that of a human there are a lot of similarities, a lot of the detailed structure that's the compartments, the organization of the brain, these principles are often shared between different species. So if you learn something in one context, you can hopefully apply it in a different context. Especially, to human development." And that, says Keller, is the ultimate goal, to gain insight on how a human brain develops and functions. He says the more we know the better equipped we will be to start tackling diseases like Alzheimers and Parkinson's.

Press CTRL+C (Windows), CMD+C (Mac), or long-press the URL below on your mobile device to copy the code

New computer software to unravel embryonic development cell by cell

Wednesday, August 06, 2014 - 02:51

Top News »

Most Popular »

Retirement »

Investing 201 »

Bond investors brace for the end of Fed stimulus Bond investors brace for the end of Fed...

Fri, Oct 10, 2014 - (4:03)

Arian Foster = BlackBerry? Arian Foster = BlackBerry?

Fri, Oct 25, 2013 - (3:16)

Don’t miss these red flags for IPOs Don’t miss these red flags for IPOs

Thu, Oct 10, 2013 - (2:34)

Copycat currency trading Copycat currency trading

Wed, Oct 02, 2013 - (2:28)

When to dump a winner When to dump a winner

Tue, Sep 24, 2013 - (1:55)

Where gold might again attract Jim Rogers Where gold might again attract Jim Rogers

Thu, Sep 19, 2013 - (2:05)

Why savings interest rates won't budge Why savings interest rates won't budge

Fri, Sep 13, 2013 - (2:09)

Buy local? ETFs try the trend Buy local? ETFs try the trend

Thu, Sep 05, 2013 - (2:42)

The better bond funds The better bond funds

Wed, Aug 07, 2013 - (2:40)

Best bargain in 40 years? European stocks Best bargain in 40 years? European stocks

Thu, Aug 01, 2013 - (2:24)

Invest like an activist Invest like an activist

Fri, Jul 26, 2013 - (2:49)

Why bruised Brazil is a buy Why bruised Brazil is a buy

Fri, Jul 19, 2013 - (2:48)

3 ways to fix your bond portfolio 3 ways to fix your bond portfolio

Thu, Jul 11, 2013 - (3:10)

The next gold? Diamonds lure investors The next gold? Diamonds lure investors

Wed, Jul 03, 2013 - (2:38)

How to play the Fed’s tapering timeline How to play the Fed’s tapering timeline

Thu, Jun 20, 2013 - (2:34)

How to play banker on the web How to play banker on the web

Tue, Jun 11, 2013 - (2:57)

3 surprises about the 2013 stock rally 3 surprises about the 2013 stock rally

Fri, May 24, 2013 - (2:11)

How to cash in on lawsuits - Investing 201 How to cash in on lawsuits - Investing 201

Tue, Apr 30, 2013 - (2:30)

Rising dollar will drive stocks higher Rising dollar will drive stocks higher

Wed, Apr 10, 2013 - (2:32)

A little-known path to big dividends - Investing 201 A little-known path to big dividends -...

Thu, Apr 04, 2013 - (3:16)

What exactly does Warren Buffett own? - Investing 201 What exactly does Warren Buffett own? -...

Thu, Feb 14, 2013 - (0:51)

Big short bets: Where are they now? - Investing 201 Big short bets: Where are they now? -...

Fri, Dec 21, 2012 - (2:33)

Money Clip »

How to get out of debt How to get out of debt

Thu, Oct 30, 2014 - (3:37)

Will Apple Pay transform mobile payments? Will Apple Pay transform mobile payments?

Thu, Oct 16, 2014 - (2:45)

3 things to do before disaster strikes 3 things to do before disaster strikes

Wed, Sep 18, 2013 - (1:39)

Your must-do money list Your must-do money list

Wed, Sep 11, 2013 - (1:24)

The worst "best" financial advice The worst "best" financial advice

Wed, Sep 04, 2013 - (1:42)

Forget gold: The case for REITs Forget gold: The case for REITs

Fri, Apr 26, 2013 - (1:19)

3 rules for buying a house now 3 rules for buying a house now

Thu, Apr 18, 2013 - (1:39)

“Stalking” your dream home - Money Clip “Stalking” your dream home - Money Clip

Wed, Mar 27, 2013 - (2:50)

3 hidden tax deductions - Money Clip 3 hidden tax deductions - Money Clip

Thu, Mar 21, 2013 - (1:33)

How to break your prenup - Money Clip How to break your prenup - Money Clip

Thu, Mar 07, 2013 - (1:18)

Watch your wallet on Pinterest - Money Clip Watch your wallet on Pinterest - Money Clip

Thu, Feb 21, 2013 - (1:33)

Get set for the big bull run - Money Clip Get set for the big bull run - Money Clip

Thu, Jan 24, 2013 - (3:41)

Moving Pictures »

Images of October Images of October

Mon, Nov 03, 2014 - (0:57)

The world in a city The world in a city

Fri, Oct 31, 2014 - (1:30)

Real-life superheroes Real-life superheroes

Tue, Oct 28, 2014 - (1:44)

Dance of the northern lights Dance of the northern lights

Mon, Oct 20, 2014 - (1:08)

Images of September Images of September

Wed, Oct 01, 2014 - (1:00)

Still missing – MH370 Still missing – MH370

Fri, Sep 05, 2014 - (2:05)

Burning Together Burning Together

Mon, Sep 01, 2014 - (2:23)

Mending dolls, teddies and hearts Mending dolls, teddies and hearts

Fri, Aug 22, 2014 - (3:12)

Images of August Images of August

Fri, Aug 29, 2014 - (1:00)

"Old timers" sail the Chesapeake Bay "Old timers" sail the Chesapeake Bay

Mon, Aug 11, 2014 - (2:27)

Burned memories Burned memories

Fri, Aug 08, 2014 - (3:02)

Images of July Images of July

Thu, Jul 31, 2014 - (1:20)

World Cup: passion on the pitch World Cup: passion on the pitch

Fri, Jul 11, 2014 - (1:00)

A refugee in America gives back A refugee in America gives back

Thu, Jul 03, 2014 - (3:25)

A long search for refuge A long search for refuge

Fri, Jun 20, 2014 - (3:04)

World Cup: Around the globe in 50 goals World Cup: Around the globe in 50 goals

Fri, Jun 06, 2014 - (1:08)

VIVID – Sydney’s spectacle of light VIVID – Sydney’s spectacle of light

Fri, May 30, 2014 - (1:37)

The week that changed Boston The week that changed Boston

Mon, Apr 14, 2014 - (3:28)

360° snapshot of life in Kabul 360° snapshot of life in Kabul

Fri, Apr 04, 2014 - (1:26)

A blind teenager, living with vision A blind teenager, living with vision

Thu, Mar 27, 2014 - (3:51)

TIMELAPSE: Backstage at the Oscars TIMELAPSE: Backstage at the Oscars

Wed, Mar 05, 2014 - (2:49)

TIMELAPSE: Lunch with Oscar nominees TIMELAPSE: Lunch with Oscar nominees

Wed, Feb 12, 2014 - (2:55)

Sochi Highlights: Let the games begin Sochi Highlights: Let the games begin

Fri, Feb 07, 2014 - (0:40)

TIMELAPSE: On the Golden Globes red carpet TIMELAPSE: On the Golden Globes red carpet

Tue, Jan 14, 2014 - (3:28)

Pictures of the Year 2013 Pictures of the Year 2013

Fri, Dec 20, 2013 - (3:03)

Marching to the beat of Sousa's drum Marching to the beat of Sousa's drum

Thu, Dec 05, 2013 - (6:11)

The Gettysburg Address The Gettysburg Address

Thu, Nov 28, 2013 - (2:31)

Making Gruyere: A family affair Making Gruyere: A family affair

Wed, Oct 16, 2013 - (5:06)

Reuters Investigates »

Where the sea is closing in Where the sea is closing in

Thu, Nov 20, 2014 - (3:41)

Re-homing victim: "I could have been dead" Re-homing victim: "I could have been dead"

Wed, Feb 19, 2014 - (8:24)

Cops and loggers in the Amazon rainforest Cops and loggers in the Amazon rainforest

Fri, Jan 10, 2014 - (4:01)

"Passed around like a dog" "Passed around like a dog"

Thu, Aug 29, 2013 - (6:32)

Adopted, then abandoned online Adopted, then abandoned online

Thu, Aug 29, 2013 - (13:22)

How the DEA keeps its secrets secret How the DEA keeps its secrets secret

Mon, Aug 05, 2013 - (1:36)

How education lost its role as the great equalizer - Reuters Investigates How education lost its role as the great...

Mon, Dec 17, 2012 - (7:52)

Jihad Jane: From abused child to American jihadist - Reuters Investigates Jihad Jane: From abused child to American...

Sat, Dec 08, 2012 - (10:02)

Jihad Jane: The order to kill - Reuters Investigates Jihad Jane: The order to kill - Reuters...

Sun, Dec 09, 2012 - (10:40)

Lessons of the Jihad Jane case - Reuters Investigates Lessons of the Jihad Jane case - Reuters...

Sun, Dec 09, 2012 - (3:43)

Exclusive: Jihad Jane in her own words Exclusive: Jihad Jane in her own words

Sat, Dec 08, 2012 - (4:11)

Attorney: How a Maryland teenager became radicalized - Reuters Investigates Attorney: How a Maryland teenager became...

Fri, Dec 07, 2012 - (4:21)

Counselor: Jihad Jane at 17 - Reuters Investigates Counselor: Jihad Jane at 17 - Reuters...

Thu, Dec 06, 2012 - (4:17)

Dateline Asia »

Chinese president's "pivot" to Australia Chinese president's "pivot" to Australia

Fri, Nov 21, 2014 - (1:59)

Landmark stock connect deal "just the beginning": HKEx CEO Landmark stock connect deal "just the...

Mon, Nov 17, 2014 - (6:39)

Could Japan GDP figures portend fresh elections? Could Japan GDP figures portend fresh...

Wed, Nov 12, 2014 - (1:42)

HKEx afloat despite lacking the Shanghai connection HKEx afloat despite lacking the Shanghai...

Fri, Nov 07, 2014 - (2:06)

Stocks soar, yen sinks on Japan stimulus shocker Stocks soar, yen sinks on Japan stimulus...

Fri, Oct 31, 2014 - (1:38)

Breakingviews: Fleeting QE gains bring emerging market pains Breakingviews: Fleeting QE gains bring...

Wed, Oct 29, 2014 - (2:05)