NEW YORK (Reuters Health) - A new study has found a “substantial” drop in U.S. men’s testosterone levels since the 1980s, but the reasons for the decline remain unclear. This trend also does not appear to be related to age.
The average levels of the male hormone dropped by 1 percent a year, Dr. Thomas Travison and colleagues from the New England Research Institutes in Watertown, Massachusetts, found. This means that, for example, a 65-year-old man in 2002 would have testosterone levels 15 percent lower than those of a 65-year-old in 1987. This also means that a greater proportion of men in 2002 would have had below-normal testosterone levels than in 1987.
“The entire population is shifting somewhat downward we think,” Travison told Reuters Health. “We’re counting on other studies to confirm this.”
Travison and his team analyzed data from the Massachusetts Male Aging Study, a long-term investigation of aging in about 1,700 Boston-area men. Data from the men were collected for three time intervals: 1987-1989, 1995-1997, and 2002-2004.
While a man’s testosterone level will fall steadily as he ages, the researchers observed a speedier decline in average testosterone levels than would have been expected with aging alone.
They hypothesized that the rising prevalence of obesity as well as the sharp decline in cigarette smoking might help explain their findings, given that testosterone levels are lower among overweight people and smoking increases testosterone levels. But these factors accounted for only a small percentage of the observed difference.
It’s likely that some sort of environmental exposure is responsible for the testosterone decline, Travison said, although he said attempting to explain what this might be based on the current findings would be “pure conjecture.”
The researchers used body mass index, the ratio of height to weight, to estimate obesity levels, he noted, but this is not a very accurate way to gauge the real adiposity, or fat content of the body, so it’s possible that obesity might be more of a factor than it appears in this analysis.
“I think like most things that are complex, it’s likely that there is no one cause,” he said.
SOURCE: Journal of Clinical Endocrinology and Metabolism, January 2007.
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